Results 31 to 40 of about 1,143,365 (261)
Dimensión Jurídica del Estado Social de Derecho
Advocatus, 2020 El presente ensayo trata, como bien lo expresa el título, sobre la dimensión jurídica del Estado Social de Derecho. Se realizará un breve pero sustancioso recorrido histórico a través de la formación del mismo resaltando en cada épo-ca la ...
Eduardo Pablo Cerra Nolasco
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Cazadoras y recolectoras. Mujeres a la búsqueda del arte [PDF]
, 2015 Actividad desarrollada en el marco de la asignatura "Introducción a la historia del arte. Dimensión social del arte", del departamento de historia del arte.
Ochando Ordóñez, Yolanda
core
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Social rights protection in times of crisis [PDF]
, 2013 Este trabajo analiza la protección de los derechos fundamentales, y en particular los derechos sociales y la dimensión social con las consecuencias de la reciente crisis económica.This work analyze fundamental rights protection, particularly social ones ...
Benlloch Domènech, Cristina +1 more
core
The political dimension of animal ethics in the context of bioethics: problems of integration and future challenges [PDF]
, 2016 Animal ethics has reached a new phase with the development of animal ethical thinking. Topics and problems previously discussed in terms of moral theories and ethical concepts are now being reformulated in terms of political theory and political action ...
Tirado, Carlos R.
core +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
REDES: Revista Hispana para el Análisis de Redes Sociales, 2008 Resumen Este trabajo refiere al estudio de las redes sociales implicadas en las estrategias de reproducción social de familias pobres, implicando tanto discusiones teóricas como análisis empíricos. En primer lugar, explicitaré los conceptos de red y de
Alicia Gutiérrez
doaj +1 more source