Results 91 to 100 of about 952,320 (325)

Fault-Tolerant Metric Dimension in Carbon Networks

Foundations
In this paper, we study the fault-tolerant metric dimension in graph theory, an important measure against failures in unique vertex identification. The metric dimension of a graph is the smallest number of vertices required to uniquely identify every ...
Kamran Azhar, Asim Nadeem, Yilun Shang
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Distance Preserving Graph Simplification

, 2011
Large graphs are difficult to represent, visualize, and understand. In this paper, we introduce "gate graph" - a new approach to perform graph simplification. A gate graph provides a simplified topological view of the original graph.
Huang, Yan, Jin, Ruoming, Ruan, Ning
core   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

A double coset ansatz for integrability in AdS/CFT

, 2012
We give a proof that the expected counting of strings attached to giant graviton branes in AdS_5 x S^5, as constrained by the Gauss Law, matches the dimension spanned by the expected dual operators in the gauge theory.
A Hashimoto, D Bekker, D Berenstein, D Berenstein, D Berenstein, D Sadri, D Vaman, DE Berenstein, F Dolan, J McGreevy, J Minahan, J Pasukonis, J Pasukonis, JM Maldacena, MT Grisaru, N Beisert, N Beisert, N Beisert, O Aharony, R Bhattacharyya, R Giles, R Mello Koch de, R Mello Koch de, R Mello Koch de, R Mello Koch de, R Mello Koch de, R Mello Koch de, R Mello Koch de, RC Read, Robert de Mello Koch, S Cordes, S Corley, S Dutta, S Ramgoolam, Sanjaye Ramgoolam, TW Brown, TW Brown, V Balasubramanian, V Balasubramanian, V Balasubramanian, V Comarmond De, W Carlson, W Fulton, Y Kimura   +43 more
core   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Edges vs Circuits: a Hierarchy of Diameters in Polyhedra [PDF]

, 2014
The study of the graph diameter of polytopes is a classical open problem in polyhedral geometry and the theory of linear optimization. In this paper we continue the investigation initiated in [4] by introducing a vast hierarchy of generalizations to the ...
Borgwardt, Steffen, De Loera, Jesús A., Finhold, Elisabeth   +2 more
core  

Beyond Blobs in Percolation Cluster Structure: The Distribution of 3-Blocks at the Percolation Threshold

, 2002
The incipient infinite cluster appearing at the bond percolation threshold can be decomposed into singly-connected ``links'' and multiply-connected ``blobs.'' Here we decompose blobs into objects known in graph theory as 3-blocks.
A. Coniglio, A. Coniglio, B. Nienhuis, C.D. Lorenz, G. Huber, G. Huber, Gerald Paul, H. Eugene Stanley, H.E. Stanley, H.J. Herrmann, J.-P. Hovi, J.E. Hopcroft, M. Aizenman, M. Porto, M.F. Gyure, M.P.M. den Nijs, P. Grassberger, P.J. Reynolds, P.N. Strenski, W. Hohberg   +19 more
core   +1 more source