Results 81 to 90 of about 501,962 (291)

Edges vs Circuits: a Hierarchy of Diameters in Polyhedra [PDF]

, 2014
The study of the graph diameter of polytopes is a classical open problem in polyhedral geometry and the theory of linear optimization. In this paper we continue the investigation initiated in [4] by introducing a vast hierarchy of generalizations to the ...
Borgwardt, Steffen, De Loera, Jesús A., Finhold, Elisabeth   +2 more
core  

First- and second-order phase transitions in Ising models on small world networks, simulations and comparison with an effective field theory

, 2010
We perform simulations of random Ising models defined over small-world networks and we check the validity and the level of approximation of a recently proposed effective field theory. Simulations confirm a rich scenario with the presence of multicritical
A. L. Ferreira, J. F. F. Mendes, M. Mézard, M. Ostilli   +3 more
core   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

The Haagerup property is stable under graph products [PDF]

, 2014
The Haagerup property, which is a strong converse of Kazhdan's property $(T)$, has translations and applications in various fields of mathematics such as representation theory, harmonic analysis, operator K-theory and so on. Moreover, this group property
Antolín, Yago, Dreesen, Dennis
core  

Most autophagic cell death studies lack evidence of causality

FEBS Open Bio, EarlyView.
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

THE LOCATING RAINBOW CONNECTION NUMBERS OF LOLLIPOP AND BARBELL GRAPHS

Barekeng
The concept of the locating rainbow connection number of a graph is an innovation in graph coloring theory that combines the concepts of rainbow vertex coloring and partition dimension on graphs.
Ariestha Widyastuty Bustan, Taufan Talib, Novita Serly Laamena, Lamanisa Rasid Saputra, Nurhayati Nurhayati   +4 more
doaj   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Universal scaling in real dimension

Nature Communications
The concept of universality has shaped our understanding of many-body physics, but is mostly limited to homogenous systems. Here, we present a study of universality on a non-homogeneous graph, the long-range diluted graph (LRDG).
Giacomo Bighin, Tilman Enss, Nicolò Defenu   +2 more
doaj   +1 more source