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Spatially aware dimension reduction for spatial transcriptomics [PDF]

open access: yesNature Communications, 2022
Spatial transcriptomics analyses can be affected by noise and spatial correlation across tissue locations. Here, the authors develop SpatialPCA, a spatially-aware dimensionality reduction method that explicitly models spatial correlation structures, and ...
Lulu Shang, Xiang Zhou
doaj   +3 more sources

Evolutionary dimension reduction in phenotypic space [PDF]

open access: yesPhysical Review Research, 2020
In general, cellular phenotypes, as measured by concentrations of cellular components, involve large number of degrees of freedom. However, recent measurement has demonstrated that phenotypic changes resulting from adaptation and evolution in response to
Takuya U. Sato, Kunihiko Kaneko
doaj   +2 more sources

Dimension Reduction for Fréchet Regression. [PDF]

open access: yesJ Am Stat Assoc, 2023
With the rapid development of data collection techniques, complex data objects that are not in the Euclidean space are frequently encountered in new statistical applications. Fréchet regression model (Peterson & Müller 2019) provides a promising framework for regression analysis with metric space-valued responses.
Zhang Q, Xue L, Li B.
europepmc   +4 more sources

Sufficient Dimension Reduction: An Information-Theoretic Viewpoint [PDF]

open access: yesEntropy, 2022
There has been a lot of interest in sufficient dimension reduction (SDR) methodologies, as well as nonlinear extensions in the statistics literature. The SDR methodology has previously been motivated by several considerations: (a) finding data-driven ...
Debashis Ghosh
doaj   +2 more sources

Spectral Dimension Reduction of Complex Dynamical Networks [PDF]

open access: yesPhysical Review X, 2019
Dynamical networks are powerful tools for modeling a broad range of complex systems, including financial markets, brains, and ecosystems. They encode how the basic elements (nodes) of these systems interact altogether (via links) and evolve (nodes ...
Edward Laurence   +3 more
doaj   +2 more sources

Dimension and Dimensional Reduction in Quantum Gravity

open access: yesUniverse, 2019
If gravity is asymptotically safe, operators will exhibit anomalous scaling at the ultraviolet fixed point in a way that makes the theory effectively two-dimensional.
Steven Carlip
doaj   +3 more sources

Dimension reduction methods for microarray data: a review

open access: yesAIMS Bioengineering, 2017
Dimension reduction has become inevitable for pre-processing of high dimensional data. “Gene expression microarray data” is an instance of such high dimensional data.
Rabia Aziz   +2 more
doaj   +2 more sources

Dimension Reduction for Efficient Data-Enabled Predictive Control [PDF]

open access: yesIEEE Control Systems Letters, 2022
In this letter, we propose a simple yet effective singular value decomposition (SVD) based strategy to reduce the optimization problem dimension in data-enabled predictive control (DeePC).
Kaixiang Zhang, Yang Zheng, Zhaojian Li
semanticscholar   +1 more source

Towards a comprehensive evaluation of dimension reduction methods for transcriptomic data visualization

open access: yesCommunications Biology, 2022
Dimension reduction (DR) algorithms project data from high dimensions to lower dimensions to enable visualization of interesting high-dimensional structure. DR algorithms are widely used for analysis of single-cell transcriptomic data. Despite widespread
Haiyang Huang   +3 more
semanticscholar   +1 more source

Joint dimension reduction and clustering analysis of single-cell RNA-seq and spatial transcriptomics data

open access: yesbioRxiv, 2021
Dimension reduction and (spatial) clustering is usually performed sequentially; however, the low-dimensional embeddings estimated in the dimension-reduction step may not be relevant to the class labels inferred in the clustering step.
Wei Liu   +7 more
semanticscholar   +1 more source

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