Results 161 to 170 of about 9,586,369 (306)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

A comparative evaluation of sufficient dimension reduction and traditional statistical methods for composite biomarker score construction in diagnostic classification. [PDF]

BMC Med Res Methodol
Ozen H, Colak E, Ozen D.
europepmc   +1 more source

Projection expectile regression for sufficient dimension reduction. [PDF]

Comput Stat Data Anal, 2023
Soale AN.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Contrastive dimension reduction: when and how? [PDF]

Adv Neural Inf Process Syst
Hawke S, Ma Y, Li D.
europepmc   +1 more source

Similarity-assisted variational autoencoder for nonlinear dimension reduction with application to single-cell RNA sequencing data. [PDF]

BMC Bioinformatics, 2023
Kim G, Chun H.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Comment on ‘Review of sparse sufficient dimension reduction’

Statistical Theory and Related Fields, 2020
Michael Declan Power, Yuexiao Dong
doaj   +1 more source

Assessing parameter identifiability of a hemodynamics PDE model using spectral surrogates and dimension reduction. [PDF]

PLoS Comput Biol
Colebank MJ.
europepmc   +1 more source

Effects of dimension reduction of hyperspectral images in skin gross pathology. [PDF]

Skin Res Technol, 2023
Aloupogianni E, Ishikawa M, Ichimura T, Hamada M, Murakami T, Sasaki A, Nakamura K, Kobayashi N, Obi T.   +8 more
europepmc   +1 more source