Results 191 to 200 of about 9,586,369 (306)

Sparse kernel sufficient dimension reduction. [PDF]

J Nonparametr Stat
Liu B, Xue L.
europepmc   +1 more source

Correspondence analysis for dimension reduction, batch integration, and visualization of single-cell RNA-seq data. [PDF]

Sci Rep, 2023
Hsu LL, Culhane AC.
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Interpretable spatially aware dimension reduction of spatial transcriptomics with STAMP. [PDF]

Nat Methods
Zhong C, Ang KS, Chen J.
europepmc   +1 more source

Translating transcriptomic findings from cancer model systems to humans through joint dimension reduction. [PDF]

Commun Biol, 2023
Price BA, Marron JS, Mose LE, Perou CM, Parker JS.   +4 more
europepmc   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

GraphPCA: a fast and interpretable dimension reduction algorithm for spatial transcriptomics data. [PDF]

Genome Biol
Yang J, Wang L, Liu L, Zheng X.
europepmc   +1 more source

Improved Interpretability of Brain-Behavior CCA With Domain-Driven Dimension Reduction. [PDF]

Front Neurosci, 2022
Liu Z, Whitaker KJ, Smith SM, Nichols TE.   +3 more
europepmc   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

PROBABILISTIC CONTRASTIVE DIMENSION REDUCTION FOR CASE-CONTROL STUDY DATA. [PDF]

Ann Appl Stat
Li D, Jones A, Engelhardt B.
europepmc   +1 more source