Results 191 to 200 of about 294,873 (258)

Supervised dimension reduction mappings. [PDF]

, 2011
Bunte, K., Biehl, M., Hammer, B.
openaire   +1 more source

Identifying heterogeneous subgroups of systemic autoimmune diseases by applying a joint dimension reduction and clustering approach to immunomarkers. [PDF]

BioData Min
Chang CW, Wang HY, Lin WY, Wang YC, Lo WL, Lin TW, Yu JR, Tseng YJ.   +7 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

BFAST: joint dimension reduction and spatial clustering with Bayesian factor analysis for zero-inflated spatial transcriptomics data. [PDF]

Brief Bioinform
Xu Y, Lv D, Zou X, Wu L, Xu X, Zhao X.
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

An encoding generative modeling approach to dimension reduction and covariate adjustment in causal inference with observational studies. [PDF]

Proc Natl Acad Sci U S A
Liu Q, Chen Z, Wong WH.
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Coexistence mechanism of ecological specialists and generalists based on a network dimension reduction method. [PDF]

Ecol Evol
Duan D, Hang J, Wu C, Bai X, Rong Y, Hou G.   +5 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Multivariate Analyses with Two-Step Dimension Reduction for an Association Study Between ¹¹C-Pittsburgh Compound B and Magnetic Resonance Imaging in Alzheimer's Disease. [PDF]

Bioengineering (Basel)
Kawaguchi A, Yamashita F.
europepmc   +1 more source