Results 141 to 150 of about 641,342 (265)

Dimensional reduction of emergent spatiotemporal cortical dynamics via a maximum entropy moment closure. [PDF]

PLoS Comput Biol, 2020
Shao Y, Zhang J, Tao L.
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Effects of Periodontitis and Jaw Morphology on Radiographic Dimensional Reduction of Anterior Mandibular Implants: A Retrospective Study. [PDF]

Int Dent J
Chen X, Xu Y, Zhang W, Wang Z.
europepmc   +1 more source

Melt crystallization mechanism analyzed with dimensional reduction of high-dimensional data representing distribution function geometries. [PDF]

Sci Rep, 2020
Nada H.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

MIAAIM: Multi-omics image integration with dimensional reduction for tissue state mapping. [PDF]

PLoS Comput Biol
Hess JM, Dzeng RK, Ilieş I, Schapiro D, Iskra JJ, Mirgh D, Nam J, Seeley EH, Verrill DE, Abdelmoula WM, Regan MS, Theocharidis G, Wu CL, Veves A, Agar NYR, Sluder AE, Poznansky MC, Sîrbulescu RF, Reeves PM.   +18 more
europepmc   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

FEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court, Nigel Francis, Andrew Shore, Stephen Rutherford   +3 more
wiley   +1 more source

Limitations of Linear Dimensional Reduction Methods in Chronic Obstructive Pulmonary Disease Phenotyping. [PDF]

Am J Respir Crit Care Med
Takefuji Y.
europepmc   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Reply to Takefuji: Limitations of Linear Dimensional Reduction Methods in Chronic Obstructive Pulmonary Disease Phenotyping. [PDF]

Am J Respir Crit Care Med
Bell AJ, Zinovyev A, Gorban AN.
europepmc   +1 more source