Results 161 to 170 of about 8,286,998 (397)

Dimensionality reduction of quality of life indicators

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2012
Selecting indicators for assessing the quality of life at the regional level is not unambigous. Currently, there are no precisely defined indicators that would give comprehensive information about the quality of life on a local level.
Andrea Jindrová, Julie Poláčková
doaj   +1 more source

On the existence of infinite-dimensional generalized harish-chandra modules [PDF]

open access: yesarXiv, 2018
We prove a general existence result for infinite-dimensional admissible (g;k)-modules, where g is a reductive finite-dimensional complex Lie algebra and k is a reductive in g algebraic subalgebra.
arxiv  

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Riemannian joint dimensionality reduction and dictionary learning on symmetric positive definite manifold [PDF]

open access: yesarXiv, 2019
Dictionary leaning (DL) and dimensionality reduction (DR) are powerful tools to analyze high-dimensional noisy signals. This paper presents a proposal of a novel Riemannian joint dimensionality reduction and dictionary learning (R-JDRDL) on symmetric positive definite (SPD) manifolds for classification tasks.
arxiv  

Confining membranes and dimensional reduction [PDF]

open access: yesJournal of High Energy Physics, 2001
14 pages, LaTeX2e, no ...
openaire   +3 more sources

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

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