Results 181 to 190 of about 529,916 (333)

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

Synthesis and crystal structure of 1-{<i>N</i>'-[(4-chloro-benzene)-sulfon-yl]carbamimido-yl}-3-phenyl-thio-urea dimethyl sulfoxide monosolvate. [PDF]

Acta Crystallogr E Crystallogr Commun
Mohamed-Ezzat RA, Elgemeie GH, Jones PG.
europepmc   +1 more source

Dimethyl Sulfoxide Protects Escherichia coli from Rapid Antimicrobial-Mediated Killing

Antimicrobial Agents and Chemotherapy, 2016
Hongfei Mi, Dai Wang, Yun-xin Xue, Zhi Zhang, Jianjun Niu, Yuzhi Hong, K. Drlica, Xilin Zhao   +7 more
semanticscholar   +1 more source

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

Advanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh, Hosni Cherif, Matthew Mannarino, Juiena Sagir, Magali Millecamps, Jean A. Ouellet, Laura S. Stone, Lisbet Haglund   +7 more
wiley   +1 more source

Dimethyl Sulfoxide Suppresses Fusarium graminearum Pathogenicity by Modulating Key Life Cycle Traits. [PDF]

Plant Pathol J
Li T, Lee S, Choi T, Lim Y, Ma T, Lee J.
europepmc   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Dimethyl Sulfoxide as a Biocompatible Extractant for Enzymatic Bioluminescent Toxicity Assays: Experimental Validation and Molecular Dynamics Insights. [PDF]

Toxics
Sutormin OS, Lonshakova-Mukina VI, Deeva AA, Gromova AA, Bajbulatov RY, Kratasyuk VA.   +5 more
europepmc   +1 more source

Crystal structure of the nucleoside 2'-de-oxy-guanosine dimethyl sulfoxide disolvate. [PDF]

Acta Crystallogr E Crystallogr Commun, 2023
Spingler B.
europepmc   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Crystal structures of the dimethyl sulfoxide solvate of 3,6-bis-(indol-3-yl)-1,4-di-methyl-piperazine-2,5-dione and of the dimethyl sulfoxide and tetra-hydro-furan solvates of 1,4-dimethyl-3,6-bis-(2-methyl-indol-3-yl)piperazine-2,5-dione. [PDF]

Acta Crystallogr E Crystallogr Commun
Padgett CW, Lynch WE, Crooke SN, Whitlock CR.   +3 more
europepmc   +1 more source