Results 141 to 150 of about 9,464 (283)

Efficacy and related factors of levonorgestrel‐releasing intrauterine system combined with metformin in fertility‐preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu, Jialu Gao, Yuxin Li, Mei Huang, Xiaoshuang Wang, Xin Zhao   +5 more
wiley   +1 more source

Young bodies, aging ovaries: A systematic review and meta‐synthesis of women's perspectives on spontaneous premature ovarian insufficiency

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objectives Spontaneous premature ovarian insufficiency (POI) is a condition characterized by the cessation of ovarian function before age 40, unrelated to medical interventions. It affects approximately 3.5% of women worldwide and can result in significant emotional, physical, and social consequences.
Maria Patricia Roman, Shaurya Aggarwal, Stergios K. Doumouchtsis   +2 more
wiley   +1 more source

Healthy eating index and risk of diminished ovarian reserve: a case–control study

Scientific Reports
Diminished ovarian reserve (DOR) is associated with reduced fertility and poor reproductive outcomes. The association between dietary patterns and DOR was not well studied.
Hatav Ghasemi-Tehrani, Gholamreza Askari, Fatemeh Zahra Allameh, Mahdi Vajdi, Reza Amiri Khosroshahi, Sepide Talebi, Rahele Ziaei, Abed Ghavami, Farzaneh Askari   +8 more
doaj   +1 more source

Decidual macrophage‐mediated ferroptosis in trophoblasts leads to recurrent spontaneous abortion

iMeta, EarlyView.
Decidual macrophages from recurrent spontaneous abortion (RSA) patients promote trophoblast ferroptosis and impair trophoblast cell function. Mechanistically, the CXCL2/NF‐κB/HMOX1 axis mediates this effect. Conversely, trophoblasts co‐cultured with RSA decidual macrophages induce pro‐inflammatory macrophage polarization through IL‐6/JAK2/STAT3 ...
Xin Chen, Xueqin Ma, Pengcheng Pang, Heng Zhou, Ruohan Li, Yan He, Yan Zhang, Jing Yang, Qianlin Song, Qingsong Ye   +9 more
wiley   +1 more source

The ovarian follicular reserve after electrosurgical treatment of ovarian endometriomas

Гинекология, 2013
Analysisofthe results of surgical treatment in 76 patients of reproductive age after endosurgicalcuration of ovarian endometriomas has revealed that monopolar coagulation diminished an ovarian follicular reserve,modern markers of which (inhibin B and ...
N V Matveeva, A E Ter-Ovakimyan, A S Gasparov   +2 more
doaj  

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Chemotherapy-induced diminished murine ovarian reserve model and impact of low-dose chemotherapy on fertility.

To establish a murine model of chemotherapy-induced diminished ovarian reserve (DOR) and investigate residual fertility after chemotherapy exposure. Two different chemotherapy protocols were tested to establish a valid DOR model by comparing follicle ...
van der Plancke, Graziella, Wen, Jen-Yu, Donnez, Jacques, Dolmans, Marie-Madeleine, Houeis, Lara, Cacciottola, Luciana   +5 more
core   +2 more sources

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Editorial: Diminished Ovarian Reserve and Poor Ovarian Response: Diagnostic and Therapeutic Management

Frontiers in Physiology, 2022
Racca Annalisa, Stoop Dominic, Polyzos Nikolaos P, Polyzos Nikolaos P   +3 more
doaj   +1 more source

Lactation, Childrearing, and Gender Justice

Journal of Applied Philosophy, EarlyView.
ABSTRACT In this article, I discuss the significance of early infant feeding choices for the goal of gender justice. Focusing on human lactation practices, I identify Exclusive Gestational Nursing (EGN) as the norm in advanced industrial societies, which creates the expectation and permission for gestators, and only gestators, to nurse children, and ...
Jenny Brown
wiley   +1 more source