Results 201 to 210 of about 791,804 (284)

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

open access: yesAllergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan   +5 more
wiley   +1 more source

Use of Autologous Exosomes to Enhance Oocyte Maturation in Patients with Diminished Ovarian Reserve: A Prospective, Randomized Clinical Trial (Pilot Study). [PDF]

open access: yesBioengineering (Basel)
Navarro Arrieta CT   +5 more
europepmc   +1 more source

Inhibition of HMGA2 Leads to Reduced Cell Proliferation and Increased Apoptosis in Human Embryonal Carcinoma Cell Lines

open access: yesAndrology, EarlyView.
ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino   +5 more
wiley   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

open access: yesAndrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Why Social Egg Freezing for Single Women Should Not Be Prohibited: A Confucian Perspective

open access: yesBioethics, EarlyView.
ABSTRACT Beginning with a recent high‐profile case in mainland China, this paper argues that the current prohibition on social egg freezing for single women cannot be justified from a Confucian ethical perspective. We first explain why Confucian ethics provides a normatively appropriate and socially salient framework for evaluating reproductive policy ...
Rui Deng, Ruiping Fan
wiley   +1 more source

Mitophagy suggesting a possible association with oocyte maturation: A study of granulosa cells from follicular fluid of normoresponder and diminished ovarian reserve cases. [PDF]

open access: yesSci Prog
Öner Ç   +10 more
europepmc   +1 more source

The Welfarist Consequentialist Case Against Conscientious Objection in Healthcare: Empirical Failures, Normative Confusions, and the Primacy of Patient Care

open access: yesBioethics, EarlyView.
ABSTRACT We have defended the view that there should be no accommodation of conscientious objectors in health care. Numerous critics have advanced arguments designed to defeat this conclusion. We respond here to what we take to be the most serious of the criticisms directed at our analysis. We begin with two distinct consequentialist lines.
J. Savulescu, U. Schuklenk
wiley   +1 more source

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