Results 111 to 120 of about 8,625 (192)

Fungal burden, dimorphic transition and candidalysin: Role in Candida albicans-induced vaginal cell damage and mitochondrial activation in vitro. [PDF]

open access: yesPLoS One
Spaggiari L   +8 more
europepmc   +1 more source

Abcc1 deficiency protects from corticosterone but not cortisol‐induced adiposity and insulin resistance in a sex‐specific manner

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A mouse model of exogenous glucocorticoid (GC) treatment was used to determine (1) if corticosterone induced the same metabolic dysregulation as cortisol, and (2) whether these differences were mediated by the corticosterone‐specific transmembrane exporter Abcc1.
Mhairi A. Paul   +9 more
wiley   +1 more source

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild   +3 more
wiley   +1 more source

Longitudinal Tracking of Astrocyte Reactivity During the Development of Chronic Orofacial Neuropathic Pain Using [18F]‐SMBT‐1 Positron‐Emission Tomography

open access: yesGlia, Volume 74, Issue 8, August 2026.
Using [18F]‐SMBT‐1 PET, we longitudinally tracked MAO‐B–expressing reactive astrocytes during orofacial neuropathic pain development in rats, revealing region‐ and time‐specific astrocyte activation during pain chronification. ABSTRACT Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an ...
Lewis S. Crawford   +14 more
wiley   +1 more source

Epigenetic‐Based Evidence for Distinct Effects of Age, Sex, and Experience in Developmental Critical Period Learning

open access: yesDevelopmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Although much is known about the encoding of experience, how the brain organizes neural circuits capable of learning and memory formation is largely unstudied. Canonical critical periods emerge from a convergence of maturation‐ and experience‐dependent processes.
Grant W. Kunzelman   +2 more
wiley   +1 more source

‘Mr. Preacherman, Should We Love Thy Neighbour?’: On Moral Understanding and Moral Change in Deep Moral Disagreements

open access: yesPhilosophical Investigations, Volume 49, Issue 3, Page 279-289, July 2026.
ABSTRACT This article examines what it means to respond, or fail to respond, to the individual realities of others in cases of deep moral disagreement concerning trans‐exclusionary sentiments. Building on a limitation we identify in Daniele Moyal‐Sharrock and Constantine Sandis' account of ‘bedrock gender’, we consider two readings of Kendrick Lamar's ...
Ryan Manhire, Salla Aldrin Salskov
wiley   +1 more source

Mascarene High Variability Shapes the Demography of a Wind‐Reliant Marine Top Predator

open access: yesGeophysical Research Letters, Volume 53, Issue 11, 16 June 2026.
Abstract Subtropical anticyclones are semi‐permanent atmospheric high‐pressure systems located in all five major ocean basins and are associated with large‐scale wind and weather patterns. They shape the physical environments of many species, yet their impacts on wildlife remain unexplored. We combined population and climate analyses to investigate the
Ruijiao Sun   +8 more
wiley   +1 more source

The Emerging Parkinson's Disease Oxylipin‐Ome

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

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