Results 11 to 20 of about 3,423,431 (180)
Pinoresinol as a Potential c-Myc Complex Modulator: An In Silico Study [PDF]
The c-Myc oncoprotein is a central regulator of oncogenic transcriptional programs that remains challenging to inhibit directly, necessitating strategies that target c-Myc–associated protein complexes rather than the protein alone.
Arnulfo Villanueva-Castillo +18 more
doaj +2 more sources
Dinámica molecular: estudio del sodio líquido A 373 K [PDF]
[spa] La Dinámica Molecular se ha desarrollado paralelamente al crecimiento de los recursos de computación. La evolución se inicia a partir de los trabajos de Alder y Wainwright en que se opera con esferas rígidas atractivas en las que se insinúa una ...
González-Miranda, J. M. (Jesús Manuel)
core +6 more sources
Análisis de las propiedades vibracionales del crotonaldehído: DFT vs MD
La dinámica molecular (MD, por sus siglas en inglés) y la teoría del funcional de la densidad (DFT, por sus siglas en inglés) son actualmente las teorías más utilizadas en ciencia computacional de materiales.
Ricardo Ruvalcaba +2 more
doaj +1 more source
Structural Analysis of SARS-CoV-2 ORF8 Protein: Pathogenic and Therapeutic Implications
Current therapeutic strategies and vaccines against SARS-CoV-2 are mainly focused on the Spike protein despite there are other viral proteins with important roles in COVID-19 pathogenicity. For example, ORF8 restructures vesicular trafficking in the host
Antonio Valcarcel +4 more
doaj +1 more source
Métodos computacionales para estimar la afinidad de un complejo ligando-receptor
A la fecha se han empleado diferentes métodos basados en la estructura para cuantificar las interacciones receptor-ligando, y a partir de estas predecir la energía libre de asociación que proporcionara un estimado de la afinidad de un compuesto por una ...
Martiniano Bello Ramírez
doaj +1 more source
Polysialic Acid in the Immune System
Polysialic acid (polySia) is a highly regulated polymer of sialic acid (Sia) with such potent biophysical characteristics that when expressed drastically influences the interaction properties of cells. Although much of what is known of polySia in mammals
Tania M. Villanueva-Cabello +5 more
doaj +1 more source
Structural adaptation of fungal cell wall in hypersaline environment
Halophilic fungi thrive in hypersaline habitats and face a range of extreme conditions. These fungal species have gained considerable attention due to their potential applications in harsh industrial processes, such as bioremediation and fermentation ...
Liyanage D. Fernando +9 more
doaj +1 more source
Spatio-Temporal Dynamics of the Patterning of Arabidopsis Flower Meristem
The qualitative model presented in this work recovers the onset of the four fields that correspond to those of each floral organ whorl of Arabidopsis flower, suggesting a mechanism for the generation of the positional information required for the ...
José Díaz +2 more
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Las enfermedades neurodegenerativas se definen como el conjunto de padecimientos que afectan a las neuronas del sistema nervioso. Ejemplos de estas enfermedades neurodegenerativas son la enfermedad de Parkinson, el Alzheimer y la Esclerosis Lateral ...
Jorge Alfonso Arvayo Zatarain +2 more
doaj +1 more source
Anthracnose caused by the hemibiotroph fungus Colletotrichum gloeosporioides is a devastating plant disease with an extensive impact on plant productivity. The process of colonization and disease progression of C.
Adriana Otero-Blanca +8 more
doaj +1 more source

