Results 41 to 50 of about 176 (86)

The role of dinoprostone for labor induction in postterm and high-risk term pregnancies

Clinical and Experimental Obstetrics & Gynecology, 2020
Purpose: To determine the effect of controlled release vaginal dinoprostone (CRVD) in post-term and high-risk term pregnancies on successful ripening, the length of active labour, the total time for delivery, route of delivery, and maternal-neonatal ...
I.F. Urunsak, U.K. Gulec, E. Eser, M. Sucu, C. Akcabay, S. Buyukkurt   +5 more
doaj   +1 more source

Spontaneous Bladder Rupture during Vaginal Delivery

Case Reports in Urology, Volume 2026, Issue 1, 2026.
Spontaneous bladder rupture during vaginal delivery is a rare yet serious complication that requires prompt recognition and management to prevent life‐threatening consequences. We report the case of a 32‐year‐old woman with a previous cesarean section who developed concurrent uterine and bladder rupture following vaginal delivery after labor induction,
Diogo Carmali, Júlia Quiterres, Sara Duarte, André Barcelos, Sónia Afonso Ramos, Inês Garcia Nunes, André Pita, Filipe Gaboleiro, Eduardo Felício, Guilherme Bernardo, Margarida Meira, Rute Branco, Andrea Furtado, Diogo Bruno, Ana Paula Santos, Ana Paula Ferreira, Fernando Ferrito, Salvatore Siracusano   +17 more
wiley   +1 more source

Intrapartum Fever—Coccidioidomycosis Diagnosed During Induction of Labor: A Case Report

Case Reports in Obstetrics and Gynecology, Volume 2026, Issue 1, 2026.
Background Coccidioidomycosis, also known as Valley fever or “cocci,” is an endemic fungal infection to southwestern United States. Coccidioidomycosis infections have an increased risk of severe disease progression in pregnancy, especially in the later trimesters and postpartum.
Ana Paula da Cunha Varella, Maique Vo, Katie Nguyen, Karuna Sharma   +3 more
wiley   +1 more source

Exploring the Role of Virtual Reality in Labor Induction: A Narrative Review of Benefits, Challenges, and Future Directions

Journal of Pregnancy, Volume 2026, Issue 1, 2026.
Background Induction of labor (IOL) is a frequent strategy to improve maternal and fetal outcomes, but both pharmacological and mechanical approaches have hazards, including uterine hyperstimulation and fetal discomfort. Objective This research investigates the potential use of virtual reality (VR) for labor induction, focusing on pain, anxiety ...
Eliannore Boutros, Mohamad Abdelkhalik, Layal Alboutary, Maria Ibrahim, Jennifer Khoury, Nidhi Chaudhary   +5 more
wiley   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Use of vaginal dinoprostone for women with term prelabor rupture of membranes and an unfavorable cervix within 6 h versus within 6–24 h

BMC Pregnancy and Childbirth
Background Most guidelines propose inducing labor within 24 h following term (37 or more weeks of gestation) prelabor rupture of membranes (PROM). However, the exact timing for initiating induction within the 24 h period remains unknown.
Lu Yuan, Guoqiang Sun, Ping Guan, Jun Chen, Bingjie Leng, Dongmei Cao   +5 more
doaj   +1 more source

Safety and effectiveness of different modes of labor induction among pregnant women delivering at referral hospitals in Dar es Salaam, Tanzania: a cohort study

BMC Pregnancy and Childbirth
Background Induction of labor is a medical procedure used to stimulate uterine contractions and promote cervical ripening, facilitating spontaneous vaginal delivery (SVD).
Emmanuel Erasto, Martine A. Manguzu, Goodluck G. Nyondo, Manase Kilonzi, Alphonce Ignace Marealle, Ritah F. Mutagonda   +5 more
doaj   +1 more source

Safety and Efficacy of Oral Mifepristone for Cervical Ripening in Single Live Intrauterine Term Unscarred Pregnancies

Journal of Pharmacy and Bioallied Sciences
Background: Mifepristone results in cervical ripening in females undergoing pregnancy termination. It causes cervical ripening via blockage of progesterone receptors. Aim: The present study aimed to assess the safety and efficacy of oral Mifepristone for
Sarika Rawat, Sheetal Hedau, Avani Ahuja, Kirti Mandloi, Sonu Rawat   +4 more
doaj   +1 more source

Comparison of the effectiveness and safety of vaginal and sublingual low-dose misoprostol versus vaginal dinoprostone for labor ınduction: A retrospective cohort study.

PLoS ONE
BackgroundLabor induction is one of the most common obstetric interventions, yet the optimal pharmacological agent and route of administration remain subjects of ongoing debate.
Elmin Eminov, Ayşe Eminov
doaj   +1 more source

Challenges and Limitations of Clinical Trials on Labor Induction: A Review of the Literature

American Journal of Perinatology Reports, 2018
Induction of labor is a common obstetric procedure performed in nearly a quarter of all deliveries in the United States. Pharmacological (prostaglandins, oxytocin) and/or mechanical methods (balloon catheters) are commonly used for labor induction ...
Oscar A. Viteri, Baha M. Sibai
doaj   +1 more source