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Results 101 to 110 of about 18,037 (266)

Screening anticancer peptides performance in organotypic prostate tumor‐stroma 3D models

International Journal of Cancer, EarlyView.
What's New? Peptide‐based drugs have emerged as promising anticancer therapies for their potential to disrupt protein–protein interactions. In this study, the authors developed a physiomimetic human 3D prostate cancer spheroid model to assess the efficacy of the CAVPENET peptide in inhibiting tumor growth. Upon incubation with CAVPENET, prostate cancer
Bárbara Matos +7 more
wiley +1 more source

Evaluating the effect of two different training interventions on improving vaginal twin birth rates and provider confidence and knowledge levels: A pre‐ and post‐intervention study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Despite the increasing trend in cesarean section rates in multiple pregnancies, vaginal delivery in twin pregnancies appears both possible and safe. Methods This retrospective multicenter study compared outcomes before and after the implementation of a vaginal twin intervention in two Italian hospitals. In January 2021 in Pescara and
Claudio Celentano +9 more
wiley +1 more source

easynem: An R package for computing and visualizing soil nematode ecological indices

iMetaOmics, EarlyView.
Easynem is a user‐friendly and flexible R package that streamlines the complex analysis of soil nematode communities for evaluating soil health. It offers an integrated workflow for data processing, calculation of dozens of ecological indices, and comprehensive visualization of results to generate meaningful ecological insights.
Kunguang Wang +8 more
wiley +1 more source

Schisantherin A: Remodeling Gut Microbiota to Activate the Gut–Immune–Neural–Adipose Axis for Thermogenesis

iNew Medicine, EarlyView.
ABSTRACT The global obesity epidemic necessitates safe and effective strategies to enhance energy expenditure. Schisantherin A (Sin A), a lignan derived from Schisandra chinensis, has demonstrated metabolic benefits, yet its systemic mechanism remains unclear.
Ling Yin
wiley +1 more source

3D‐Printed Models in Oral Surgery Simulation Training: A Scoping Review

Journal of Dental Education, EarlyView.
ABSTRACT Background Advancements in three‐dimensional (3D) printing have introduced innovative tools for medical and dental education. In dental surgery, 3D‐printed simulation models offer valuable presurgical training. This review explores the scope, study types, key findings, limitations, and future research needs to enhance their application in ...
Shahrzad Rahimizadeh Nahavandi +5 more
wiley +1 more source

Cardioprotective effect of spirulina on cafeteria diet‐induced cardiac injury in silico and in vivo study

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Obesity is a major risk factor for cardiovascular disease, primarily due to its effects on lipid metabolism, oxidative stress, and inflammation. The aim of this study was to evaluate the effects of spirulina (SP) on cafeteria diet (CD)‐induced myocardial oxidative stress and inflammation using biochemical, histological, and in ...
Fatma Arrari +3 more
wiley +1 more source

Association Between Colorectal Cancer Screening and Survival in Patients Older Than 70 Years: Results of A National Multicenter Retrospective Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Colorectal cancer screening mainly targets a population between 50 and 70 years of age; however, it is inconsistently implemented in people over 70. The aim of this study was to analyze the association between colorectal cancer (CRC) screening, postoperative mortality, and perioperative and oncologic outcomes in a large population ...
Matteo Rottoli +499 more
wiley +1 more source

Ultrafast Electro‐Optical Response of Polymer‐Dispersed Liquid Crystals with Ferroelectric Nematic Liquid Crystal in Light Transmission to Light Scattering Switching

Macromolecular Materials and Engineering, EarlyView.
Polymer‐dispersed liquid crystals (PDLCs) are electro‐optical functional materials capable of switching between light‐transmitting and light‐scattering states. We successfully fabricated a PDLC for the first time using ferroelectric nematic liquid crystal (FNLC) with high polar and spontaneous polarization.
Raita Takahashi +5 more
wiley +1 more source

Retatrutide Shows Multiple Metabolic Benefits in Diet‐Induced Obese MASH Mouse and Hamster Models

Obesity, EarlyView.
ABSTRACT Objective/Methods Our aim was to evaluate the efficacy of the triple glucagon, GIP, and GLP‐1 receptor agonist retatrutide in diet‐induced obese MASH mouse and hamster models, two preclinical models that we routinely use for assessing new therapies targeting obesity.
François Briand +6 more
wiley +1 more source

Optimization of Microfluidic Geometry for Extracellular Vesicle Capture Using an Automated Parallel Pattern Search

PROTEOMICS, EarlyView.
ABSTRACT Microfluidic affinity‐based capture of extracellular vesicles (EVs) holds great promise for disease diagnostics and monitoring therapeutic EV production. However, optimizing microfluidic channel geometries for efficient EV capture remains understudied due to the effort required to experimentally test numerous designs.
Arvin Lim +6 more
wiley +1 more source

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