Results 131 to 140 of about 18,037 (266)

AMSC‐sEVs Ameliorated Crohn's Disease by Inhibiting Macrophage‐Myofibroblast Transition Through the Delivery of MFGE8

open access: yesCell Proliferation, EarlyView.
Our study demonstrated that TGF‐β1 activated MAPK signalling pathway and promoted the MMT and secretion of CCL17 under CD‐associated intestinal inflammatory conditions. AMSC‐sEVs can deliver MFGE8, which inhibits MMT and CCL17‐mediated Treg recruitment by suppressing the MAPK signalling pathway, thereby alleviating intestinal fibrosis.
Minghao Xie   +6 more
wiley   +1 more source

Cellular Morphometric Analysis (CellMorph)—a comprehensive imaging‐based tool for quantifying cellular phenotype heterogeneity and dynamics across biological processes

open access: yesThe FEBS Journal, EarlyView.
CellMorph is a groundbreaking tool that allows researchers to analyze multiple features from single cells, including cell size and shape, cytosolic staining and subcellular texture, nuclear staining, and morphometry. By evaluating images from both bright‐field and fluorescence microscopy, it also tracks changes in living cells during key processes such
Henrique Quaiato de Oliveira   +16 more
wiley   +1 more source

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala   +14 more
wiley   +1 more source

Information Distortion in Electronic Health Records: A Concept Analysis

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims To conceptualise information distortion in Electronic Health Records (EHRs), with the goal of providing a theoretical foundation for improving documentation practices. Design A concept analysis. Methods Walker and Avant's strategy for concept analysis was used. The defining attributes, antecedents and consequences were identified.
Jianan Wang   +5 more
wiley   +1 more source

How Context Shapes Person‐Centred Fundamental Care Through Nurse–Patient Relationships: Validation of the FoC Intelligence Modelling Tool and Predictive Pathway Analysis

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Background The Fundamentals of Care (FoC) Framework emphasises that care quality depends not only on clinical tasks but also on interpersonal relationships and the organisational context in which care is delivered. Although patient‐reported outcome and experience measures (PROMs and PREMs) have gained relevance in capturing these aspects ...
Regina Allande‐Cussó   +5 more
wiley   +1 more source

Epidemiology and allergen sensitisation in patients undergoing prick testing. [PDF]

open access: yesWorld Allergy Organ J
Monge Ortega OP   +2 more
europepmc   +1 more source

The Information Content of Operational Effectiveness

open access: yesJournal of Business Finance &Accounting, EarlyView.
ABSTRACT We address whether and why a firm's operational effectiveness, OpEff$\textit{OpEff}$, has information content for investors and what role that information plays in the price discovery process at quarterly earnings announcements. We measure OpEff$\textit{OpEff}$ using the cash conversion cycle (CCC) multiplied by −1, such that higher OpEff ...
Mary E. Barth   +2 more
wiley   +1 more source

[Pharmacokinetic interaction between linezolid and rifampicin: A case report]. [PDF]

open access: yesRev Esp Quimioter
Fernández-Vázquez A   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy