Results 131 to 140 of about 18,674 (267)

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

The changes in perceived self-efficacy, academic engagement, and empathy following simulation-based learning among undergraduate physiotherapy students: a quasi-experimental study. [PDF]

BMC Med Educ
Ochandorena-Acha M, Jolis-Prat R, Escribà-Salvans A, Oliveira VR, Rierola-Fochs S, Parés-Martínez C, Terradas-Monllor M.   +6 more
europepmc   +1 more source

Amylin analogues as a novel perspective in anti‐obesity therapy

British Journal of Pharmacology, EarlyView.
Abstract Public health systems face a major challenge because of the worldwide obesity epidemic. The number of obese individuals has increased dramatically and, even in Switzerland which may be considered a relatively “lean” country, the numbers are alarmingly high and have reached almost 50% of the adult population.
Thomas A. Lutz
wiley   +1 more source

Inconsistencies in the Assessment of Endodontic Outcomes in Patients with Special Health Care Needs: A Novel Proposal. [PDF]

Diagnostics (Basel)
Diz Dios P, Souto Míguez A, García-Caballero L, García Mato E, Diniz-Freitas M, Rivas Mundiña B.   +5 more
europepmc   +1 more source

Re‐thinking peripheral dysfunctions in obesity: The emerging role of sulphaceutics and sulphanutraceutics

British Journal of Pharmacology, EarlyView.
Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo, Veronica Casale, Roberta d'Emmanuele di Villa Bianca, Valentina Vellecco, Mariarosaria Bucci   +4 more
wiley   +1 more source

Unusual White Plaques on the Tongue in a 37-Year-Old Male. [PDF]

Clin Case Rep
García Iglesias JR, Diz-Dios P, Limeres-Posse J, Diniz-Freitas M.   +3 more
europepmc   +1 more source

"Parola di Dio, parola a Dio". Aproccio spirituale

Revista Catalana de Teologia, 2008
Prayer comes from faith. Our listening to the word of God and our addressing ourselves to God in our own words depend on faith and our only certainty is embedded in the field of Faith. And that determines that the language of prayer can only be steeped in humility. Faith in Christ can speak no other language but that of humility.
openaire   +1 more source

A covalent peptide engager approach to equip immunotherapeutic monoclonal and pan IgG serum antibodies with new tumour‐targeting function

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Site‐specific antibody modification is a useful chemical strategy to elaborate antibody therapeutic function. Conventional lysine‐ or cysteine‐based conjugation methods generate heterogeneous products, while protein engineering approaches are resource‐intensive.
Karolina Krygier, Sandra Szu‐Wei Hwang, Anthony F. Rullo   +2 more
wiley   +1 more source

Ketoconazole for Cutaneous Leishmaniasis in the Context of Drug Shortages: A Case Report from Madre de Dios, Peru. [PDF]

Yale J Biol Med
Vásquez-Paredes PJ.
europepmc   +1 more source

Periodontitis‐Associated Circulating EVs Promote Colorectal Cancer Progression via Carnosine‐Mediated Acidosis Adaptation

Cell Proliferation, EarlyView.
This study identifies a link between periodontitis and CRC progression mediated by carnosine‐enriched circulating EVs. These EVs target the intestine and elevate tumour cell intracellular pH (pHi), which rescues lysosomal function. This process drives a transition from dysfunctional lysosomes to functional ones, promoting a high malignancy phenotype in
Ruoyi Wu, Zihan Cai, Hualing Sun, Haikun Yu, Bicheng Zhang, Chi Zhang, Yi Fan, Xiaoxuan Zhu, Yueqi Ni, Yu Cui, Kaixin Wang, Zhe Li, Xinyi Zhou, Qing He, Yanru Wu, Yufeng Zhang   +15 more
wiley   +1 more source