Results 191 to 200 of about 18,037 (266)

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

MitoNGS: an online platform to analyze fish metabarcoding data in high resolution. [PDF]

Mol Biol Evol
Zhu T, Sato Y, Fukunaga T, Miya M, Iwasaki W, Yoshizawa S.   +5 more
europepmc   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, Volume 13, Issue 14, 9 March 2026.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Evolution of mortality rates due to gastrointestinal bleeding in Peru and its geographic areas, 2003-2022. [PDF]

BMC Gastroenterol
Ortiz-Alfaro MA, Vizcarra-Díaz JC, Rudas-Sulca B, Alegre-Cordero I, Damjanovic-Burga Y, Poterico JA, Ybaseta-Medina J, Tasayco-Marquez LM, Torres-Roman JS.   +8 more
europepmc   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Coach-Perpetrated Interpersonal Violence: Witnessing, Perceived Harmfulness and the Role of Coaching Motivational Climate. [PDF]

Eur J Sport Sci
Chroni SA, Hassandra M, Verhelle H, Alexopoulos A, de Dios Benítez-Sillero J, Calmaestra J, Hansen PØ, Kerr-Cumbo R, Lara-Bercial S, Navarro A, Nery M, Nicolini C, Santos T, Skille EÅ, Vivirito S, Vertommen T.   +15 more
europepmc   +1 more source

Endothelial Cell‐Based Vascular Bandages for Blood–Brain Barrier Repair and Targeted siRNA Delivery

Advanced Science, Volume 13, Issue 13, 3 March 2026.
mECs restore blood–brain barrier function after cerebral ischemia–reperfusion by simultaneously targeting, supporting, and regulating the damaged vasculature. mECs home to injured cerebral vessels through interactions with highly expressed VLA‐4, reinforce endothelial integrity by forming new junctions, and, upon OGD‐SN treatment, acquire enhanced ...
Yaosheng Li, Yunfei Dong, Yaode He, Juanjuan Zheng, Hui Liu, Lu Li, Xiaoxu Hao, Yanli Zhao, Zefeng Yang, Yuankai Sun, Zhiwei Du, Bo Zhao, Weihang Zhou, Honghui Wu, Tianyuan Zhang, Jiahe Wu, Xiangrui Liu, Xianzhen Yin, Zhicai Chen, Rui Xue, Min Lou, Zhen Gu, Xinchi Jiang, Jianqing Gao   +23 more
wiley   +1 more source

Solution‐Processed Organic Photovoltaics: Fabrication Advances and Challenges

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review highlights recent advances in organic photovoltaic (OPV) device fabrication, emphasizing how material selection, interface engineering, and scalable processing techniques shape device performance. It discusses progress in photoactive and charge transport layers, electrode optimization, and large‐area manufacturing, offering insights into ...
Kerui Liu, Chenyujie Zhu, Yuanyuan Jiang, Feng Liu, Xiaozhang Zhu   +4 more
wiley   +1 more source

The gauze that time forgot: unmasking a liver mass and the surgical lessons etched in cotton. [PDF]

J Surg Case Rep
Medinilla M, Lopez-Valdes S, Diaz Q C, Henry D.   +3 more
europepmc   +1 more source

Commentary: Physiological effects of bi-level high-flow nasal cannula in healthy individuals: a proof of concept trial. [PDF]

Front Med (Lausanne)
Gallardo A, Díaz-Cabrera A, Castro-Sayat M.   +2 more
europepmc   +1 more source