Results 181 to 190 of about 25,787 (305)

Hypoxia Preserves Chromatin Integrity and Delays Cellular Senescence through Epigenetic Regulation. [PDF]

Biomol Ther (Seoul)
Park C, Park H.
europepmc   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Beyond energy: how TCA cycle-derived metabolites regulate gene expression and inflammation in the nucleus. [PDF]

J Inflamm (Lond)
Randhawa J, Pålsson-McDermott EM.
europepmc   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Functional characterization of SDHB variants: Advancing succinate dehydrogenase biology and variant curation in hereditary paraganglioma. [PDF]

J Clin Invest
Clifton-Bligh R.
europepmc   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Probing the Mechanism of l‑DOPA 2,3-Dioxygenase Using Synthetic Derivatives of 3,4-Dihydroxyhydrocinnamic Acid. [PDF]

ACS Omega
Demisew AT, Cohen JR, Gruss EG, Bui JD, Steiner JL, Xhafkollari G, Marasco RN, Betonio M, Strzeminski D, Leyes Porello S, Colabroy KL, Peterson LW.   +11 more
europepmc   +1 more source

Three closely linked X‐chromosomal genes potentially control sex determination in Cannabis sativa

New Phytologist, EarlyView.
Summary Sex determination mechanisms in dioecious plants remain poorly understood yet offer an excellent model system to study genetic changes underlying morphological evolution. We investigated the genetic basis of sex determination in Cannabis sativa, combining quantitative trait locus mapping in a segregating population, comparative transcriptomics ...
Matteo Toscani, Afsheen Malik, Ainhoa Riera‐Begue, Caroline A. Dowling, Quentin Rougemont, Ricardo C. Rodríguez de la Vega, Tatiana Giraud, Susanne Schilling, Rainer Melzer   +8 more
wiley   +1 more source

Substrate Epoxidation Catalyzed by the Nonheme Iron Dioxygenase Dapdiamide Biosynthesis Enzyme C. Why Is the Substrate Tethered? [PDF]

Chemistry
Cao J, de Visser SP.
europepmc   +1 more source

Cytokinin downregulates Photosystem II photochemistry during prolonged darkness in a phytochrome B‐dependent manner

New Phytologist, EarlyView.
Cytokinin–phyB signaling modulates PSII photochemistry during prolonged darkness. Summary Cytokinins (CKs) delay dark‐induced senescence, but how they tune photosynthetic function in darkness remains unclear. We investigated the effects of classical aromatic CK benzylaminopurine and CK‐derived compound 1‐(2‐methoxyethyl)‐3‐(1,2,3‐thiadiazol‐5‐yl)urea ...
Veronika Kábrtová, Zuzana Kučerová, Ivo Chamrád, René Lenobel, Pavel Roudnický, Jan Skalák, Martin Hudeček, Filip Zavadil Kokáš, Marek Rác, Tereza Vánská, Jaroslav Nisler, Jan Hejátko, Miroslav Strnad, Martina Špundová, Ondřej Plíhal   +14 more
wiley   +1 more source