Results 171 to 180 of about 66,268 (303)

Machine Learning Exploration of Food-Derived Chemical Space for Potential Nutritional Metabolic Regulators Targeting Dipeptidyl Peptidase-4. [PDF]

Pharmaceuticals (Basel)
Alzunaidy NA.
europepmc   +1 more source

Sustained glucagon-like peptide-1 receptor agonist treatment improves glycemic control and reduces all-cause mortality compared to dipeptidyl peptidase-4 inhibitors: A real-world target trial emulation in type 2 diabetes. [PDF]

Diabetes Obes Metab
Abstract Background Glucagon‐like peptide 1 receptor agonists (GLP‐1 RAs) improve glycemic outcomes in people with type 2 diabetes, but their generalizability to routine clinical practice remains uncertain. Aim To evaluate the real‐world effectiveness of sustained GLP‐1 RA use on haemoglobin A1c (HbA1c) over 1 to 4.5 years, using dipeptidyl peptidase 4
Sørensen KK, Yazdanfard PDW, Zareini B, Wood-Kurland HK, Pedersen-Bjergaard U, Andersen MP, Michelsen J, Imberg H, Lind M, Hallström S, Lanzinger S, Munch A, Ohlendorff JS, Gerds TA, Torp-Pedersen C, REDDIE Consortium.   +15 more
europepmc   +2 more sources

Dipeptidyl Peptidase-4 Activity Measurement [PDF]

, 2020
openaire   +1 more source

Targeting Middle East Respiratory Syndrome Coronavirus Spike Fusion Machinery With Antiviral Peptides: In Silico Exploration of the Heptad Repeat 2 Domain

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Griffithsin, Brevinin‐2, and CCL20 were identified as potent MERS‐CoV fusion inhibitor candidates targeting the HR2 domain through integrated molecular docking, MD simulations, and MM/PBSA analyses. These peptides demonstrated superior binding stability and favorable safety profiles compared to the standard inhibitor, supporting their potential as ...
Nasser Alotaiq, Doni Dermawan, Samir Chtita   +2 more
wiley   +1 more source

Case report: Epidermolysis bullosa acquisita following dipeptidyl peptidase-4 inhibitor therapy and complicated by immune thrombocytopenic purpura. [PDF]

Front Immunol
Kawamoto H, Sasaki N, Ueda Y, Ishii N, Sawada Y.   +4 more
europepmc   +1 more source

DPP4 in diabetes [PDF]

, 2015
Diana Röhrborn
core   +1 more source

Phytotherapeutic Regulation of Matrix Metalloproteinases in Diabetic Foot Ulcer: Molecular Mechanisms and Wound Healing Perspectives

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
Chronic inflammation in diabetic foot ulcers elevates MMP activity and suppresses TIMP and growth factor signaling, impairing tissue repair. Phytochemicals modulate NF‐κB/MAPK pathways and enhance Nrf2–TIMP expression, restoring MMP/TIMP balance, promoting collagen deposition, angiogenesis, and re‐epithelialization, leading to effective wound healing ...
Vishnu Priyan Elaiyaraja, Eswara Rajagopal, Subhikssha Babu, Balaji Sadhasivam   +3 more
wiley   +1 more source

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini, Hassan Valadbeigi, Seyedeh Mahdieh Khoshnazar, Saeed Khoshnood, Shahab Falahi, Delsuz Rezaee, Ali Hematian, Mohammad Hossein Haddadi   +7 more
wiley   +1 more source

Effects of dipeptidyl peptidase‐4 inhibition in vivo: Dipeptidyl peptidase‐4 inhibitor/gut microbiome crosstalk suggests novel therapeutic options for diabetes management

Journal of Diabetes Investigation
Takuma Yasuda, Norio Harada, Nobuya Inagaki   +2 more
doaj   +1 more source

Identification of distinct epitopes in dipeptidyl peptidase-4 inhibitor-associated bullous pemphigoid. [PDF]

Sci Adv
Mai S, Mai Y, Ujiie I, Izumi K, Natsuga K, Nishie W, Ujiie H.   +6 more
europepmc   +1 more source