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Context-dependent effects of dipeptidyl peptidase 4 inhibitors
Current Opinion in Nephrology and Hypertension, 2016The antidiabetic mechanism of dipeptidyl peptidase 4 (DPP4) inhibitors is attributed to attenuation of incretin metabolism. Because DPP4 has at least 45 substrates, context-dependent off-target effects of DPP4 inhibitors are likely. Here, we consider the clinical ramifications of the context-dependent effects of DPP4 inhibitors.Although incretins ...
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Dipeptidyl Peptidase 4 Inhibition for Prophylaxis of Acute Graft-versus-Host Disease
New England Journal of Medicine, 2021Sherif S Farag +2 more
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Cardiovascular effects of dipeptidyl peptidase-4 inhibitors.
Hippokratia, 2016Dipeptidyl peptidase-4 (DPP-4) inhibitors are effective glucose-lowering agents that do not increase body weight and are associated with a low risk for hypoglycemia. Also, they appear to exert beneficial effects on other established cardiovascular risk factors, including dyslipidemia and hypertension.
M, Papagianni, K, Tziomalos
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Diabetes and Metabolic Syndrome: Clinical Research and Reviews, 2021
Iis Inayati Rakhmat +2 more
exaly
Iis Inayati Rakhmat +2 more
exaly
Inhibitors of Dipeptidyl Peptidase 4
2005Stephen L. Gwaltney, Jeffrey A. Stafford
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