Results 11 to 20 of about 65,815 (207)

Role of Dipeptidyl Peptidase 4 Inhibitors in Antidiabetic Treatment

Molecules, 2022
In recent years, important changes have occurred in the field of diabetes treatment. The focus of the treatment of diabetic patients has shifted from the control of blood glucose itself to the overall management of risk factors, while adjusting blood ...
Ruili Yin, Yongsong Xu, Xin Wang, Longyan Yang, Dong Zhao   +4 more
doaj   +1 more source

Dipeptidyl peptidase 4 inhibitors in modern domestic practice

Медицинский совет, 2020
The choice of treatment of diabetes mellitus type 2 is personalized, based on modern Russian and international algorithms for management of such patients.
A. S. Ametov, N. A. Chernikov, O. A. Knyshenko   +2 more
doaj   +1 more source

SARS-CoV-2 and diabetes: A potential therapeutic effect of dipeptidyl peptidase 4 inhibitors in diabetic patients diagnosed with COVID-19

Metabolism Open, 2021
COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 and has become an urgent economic and health challenge. Dipeptidyl peptidase 4 (DPP4), also mentioned as a cluster of differentiation 26 (CD26) is a serine exopeptidase found in two ...
Zemene Demelash Kifle, Alem Endeshaw Woldeyohanin, Chilot Abiyu Demeke   +2 more
doaj   +1 more source

Solvent and thermal stability, and pH kinetics, of proline-specific dipeptidyl peptidase IV-like enzyme from bovine serum [PDF]

, 2007
Proline-specific dipeptidyl peptidase-like (DPP IV; EC 3.4.14.5) activity in bovine serum has attracted little attention despite its ready availability and the paucity of useful proline-cleaving enzymes.
Abbott, Barry, Brendan F. O’Connor, Buckley, Bušek, Chruscinska, Ciarán Ó’Fágáin, De Meester, Deborah M. Ruth, Demuth, Dixon, Duke-Cohan, Dunn, Durinx, Edens, Engel, Fersht, FitzGerald, Gonzalez, Gorren, Grasso, Jagath, Khmelnitsky, Kikkawa, Lambeir, Lee, Maes, Mentlein, Mittal, Ogino, Ohkubo, Ohnishi, O’Cuinn, Poltorak, Poltorak, Rasmussen, Sears, Sentandreu, Sheehan, Smith, Séamus J. Buckley, Trubetskoy, Yaron, Yoshimoto   +43 more
core   +1 more source

DPP4 (dipeptidyl-peptidase 4) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2013
Review on DPP4 (dipeptidyl-peptidase 4), with data on DNA, on the protein encoded, and where the gene is implicated.
Ohnuma, K, Morimoto, C
openaire   +2 more sources

Increasing Age Associated with Higher Dipeptidyl Peptidase-4 Inhibition Rate Is a Predictive Factor for Efficacy of Dipeptidyl Peptidase-4 Inhibitors [PDF]

Diabetes & Metabolism Journal, 2022
Background It is not known which type 2 diabetes mellitus (T2DM) patients would most benefit from dipeptidyl peptidase-4 (DPP-4) inhibitor treatment.
Sangmo Hong, Chang Hee Jung, Song Han, Cheol-Young Park   +3 more
doaj   +1 more source

Comparing treatment intensification and clinical outcomes of metformin and dipeptidyl peptidase‐4 inhibitors in treatment‐naïve patients with type 2 diabetes in Japan

Journal of Diabetes Investigation, 2020
Japan's guidelines emphasize tailored therapy, but do not guide physicians on the use of a specific regimen in drug‐naive patients. The role of long‐term initial therapy could be important in key elements of diabetes treatment, such as continuation of ...
Takeshi Horii, Makiko Iwasawa, Jyunichi Shimizu, Koichiro Atsuda   +3 more
doaj   +1 more source

Total tissue lactate dehydrogenase activity in endometrial carcinoma [PDF]

, 2008
Lactate dehydrogenase (LDH) is essential for continuous glycolysis necessary for accelerated tumor growth. The aim of this study was to reconsider if assay of total tissue activity of this enzyme could be useful as marker for endometrial carcinoma (EC ...
Abramić, Marija, Babić, Damir, Ilić-Forko, Jadranka, Osmak, Maja, Šimaga, Šumski   +4 more
core   +1 more source

The purification and characterisation of novel dipeptidyl peptidase IV-like activity from bovine serum [PDF]

, 2004
The discovery of a potentially novel proline-specific peptidase from bovine serum is presented which is capable of cleaving the dipeptidyl peptidase IV (DPIV) substrate Gly-Pro-MCA.
Abbott, Birney, Cunningham, De Meester, De Meester, Duke-Cohan, Duke-Cohan, Duke-Cohan, Durinx, Gilmartin, Hegen, Hopsu-Havu, Huang, Iwaki-Egawa, Kin, Laemmli, Malik, Mentlein, Mentlein, Ohkubo, Ohnishi, Pineiro-Sanchez, Scanlan, Schon, Sedo, Sedo, Shibuya-Saruta, Smith, Stockel-Maschek, Underwood, Yaron, Yoshimoto   +31 more
core   +1 more source

An updated systematic review and meta-analysis on the efficacy and tolerability of dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes with moderate to severe chronic kidney disease

SAGE Open Medicine, 2016
Objective: This updated meta-analysis determines the effect of dipeptidyl peptidase-4 inhibitors on glycemic and tolerability outcomes in patients with type 2 diabetes mellitus and chronic kidney disease with glomerular filtration rate of ⩽60 mL/min or ...
Devada Singh-Franco, Catherine Harrington, Eglis Tellez-Corrales   +2 more
doaj   +1 more source