Results 221 to 230 of about 13,714 (298)
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DIPHOSPHONATES AND PAINFUL FEET
Australian and New Zealand Journal of Medicine, 1983Abstract: Localised foot pain occurred in four patients with Paget's disease of bone or myositis ossificans who were treated with disodium etidronate (EHDP) in a dose of 10 to 20 mg/kg body weight/day for four to six months. There was localised tenderness and sometimes slight swelling at the painful areas.
R A, Evans, D, MacDonald
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Diphosphonate Therapy in Nephrocalcinosis
British Journal of Urology, 1976The inhibiting effect of diphosphonates on calcification in tissues has led to their successful use i n conditions associated with abnormal calcification, such as niyositis ossificans (Bassett et al. , 1969; Cram et al.
D A, McCredie, H R, Powell, E, Rotenberg
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Diphosphonate Treatment of Paget's Disease
Clinical Orthopaedics and Related Research, 1976Ethane-1-hydroxy-1, 1-diphosphonate (EHDP) was administered in a dose of 20 mg/kg/d to 21 patients with symptomatic Paget's disease. All patients were treated for 6 months and then followed for an additional 6 months. There was a striking decline in serum alkaline phosphatase and urinary hydroxy-proline excretion observed after 3 months of therapy ...
G A, Finerman +3 more
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Diphosphonate Treatment of Calcinosis Universalis
New England Journal of Medicine, 1971CALCINOSIS universalis is a condition characterized by progressive accumulation of amorphous calcium phosphate and crystalline hydroxyapatite in subcutaneous lesions. The etiology is not known. Numerous modes of therapy have been proposed, including increased dietary phosphate, a diet low in calcium and high in phosphorus, a ketogenic diet, infusions ...
R L, Cram +3 more
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[Treatment with diphosphonates].
La Clinica terapeutica, 1980---
ZAVAGLI, Giorgio +2 more
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99MTc-diphosphonate uptake in neuroblastoma
American Journal of Roentgenology, 1976Marked uptake of 99mTc-diphosphonate was noted in an extraadrenal neuroblastoma. Calcification was not demonstrable on radiographic or light microscopic examination, nor was crystalline material identified on electron microscopic examination; capillaries in the lesion appeared to be intact.
W, McCartney +4 more
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New diphosphonate compounds for skeletal imaging: comparison with methylene diphosphonate.
Radiology, 1983Three-hour biodistribution of Tc-99m complexes of six diphosphonates was compared in rabbits with tibial lesions to determine which was best for detection of focal bone lesions. Sr-85 was used as a standard. N,N-dimethylaminomethylene diphosphonate (DMAD) was the only agent with a higher lesion/normal bone ratio than methylene diphosphonate (MDP ...
G, Subramanian +5 more
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Synthesis of Glycerol-1,3-diphosphonic Acid
Canadian Journal of Biochemistry, 1973The synthesis of glycerol-1,3-diphosphonic acid, the phosphonic acid analogue of the naturally occurring glycerol-1,3-diphosphoric acid, is described. The phosphonic acid analogue was obtained in an overall yield of 29.7%, by heating a mixture of 1,3-dibromo-2-hexadecanoyloxypropane and triethyl phosphite to 140° for 48 h, distilling off in vacuo the ...
R, Robinson, E, Baer
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Some aliphatic diphosphonic tetrachlorides. Part II. Some reactions of diphosphonic tetrachlorides
Journal of the Chemical Society C: Organic, 1967Aliphatic diphosphonic tetrachlorides and Grignard reagents containing aryl groups readily gave diphosphine dioxides, of which several are described. In a similar reaction of the tetrachlorides with Grignard reagents containing branched alkyl groups the products were not the expected diphosphine dioxides, but the products of mono-substitution at each ...
Gennady M. Kosolapoff, Alfred D. Brown
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Benign myocardial uptake of hydroxymethylene diphosphonate
Nuclear Medicine Communications, 1994During 'routine' bone scanning with diphosphonates, 10 elderly men were noted to show prominent myocardial uptake of Tc-hydroxymethylene diphosphonate (HDP) consistently, but no heart activity was seen with Tc-methylene disphosphonate (MDP). None had evidence of recent myocardial injury and the uptake persisted over a period of many months.
A, Jones, D, Keeling
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