Results 131 to 140 of about 288,937 (288)

Multicolor interband solitons in microcombs. [PDF]

Light Sci Appl
Ji QX, Hou H, Ge J, Yu Y, Gao M, Jin W, Guo J, Wu L, Liu P, Feshali A, Paniccia M, Bowers J, Vahala K.   +12 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Widely tunable and narrow-linewidth violet lasers enabled by UV-transparent materials. [PDF]

Nat Commun
Franken CAA, Hendriks WAPM, Winkler LV, do Nascimento AR, van Rees A, Dijkstra M, Mardani S, Kienzler D, Dekker R, van Kerkhof J, van der Slot PJM, García-Blanco SM, Boller KJ.   +12 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

A large-scale coherent 4D imaging sensor. [PDF]

Nature
Settembrini FF, Gungor AC, Forrer A, Fortune SA, Dell'Aquila A, Padmanabhan P, Opris IE, Sotto M, Dordevic N, Perelman Y, Christen T, Wang M, Nicolaescu R.   +12 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Thin film lithium niobate on sapphire for integrated mid-infrared modulator. [PDF]

Nat Commun
Didier P, Jain P, Bertrand M, Kellner J, Pitz O, Dai Z, Kuttner T, Beck M, Chen B, Faist J, Grange R.   +10 more
europepmc   +1 more source

The Study of Direct-Coupled Magnetic Amplifier with the Thyratron

The Study of Direct-Coupled Magnetic Amplifier with the Thyratron
application/pdf Bulletin of University of Osaka Prefecture. Series A, Engineering and natural sciences.
openaire  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Nonlinearity- and Dispersion-Controlled High-Energy All-Fiber Femtosecond Laser System with Peak Power Exceeding 0.5 GW. [PDF]

Nanomaterials (Basel)
Li F, Li Q, Xing J, Cao X, Wen W, Wang L, Wei Y, Zhao H, Wang Y, Fu Y, Zhao W.   +10 more
europepmc   +1 more source