Results 81 to 90 of about 288,937 (288)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Direct reading inductance meter [PDF]
, 1977 A direct reading inductance meter comprised of a crystal oscillator and an LC tuned oscillator is presented. The oscillators function respectively to generate a reference frequency, f(r), and to generate an initial frequency, f(0), which when mixed ...
Kolby, R. B.
core +1 more source
THE DEVELOPMENT OF A DIRECT COUPLED, TRANSISTORIZED, SUB-MILLIMICROAMPERE CURRENT AMPLIFIER [PDF]
, 1961 Development of a direct coupled, transistorized current amplifler is reported with sensitivities extending below the millimicroampere region of input currents. The amplifier employs a shunt feedback and exhibits reproducible characteristics. Discovery of this special effect and the design and testing employed in the incorporation of transistors into ...
openaire +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Polarization diversity monopulse tracking receiver Patent [PDF]
, 1967 Polarization diversity monopulse tracking receiver design without radio frequency ...
Taylor, R. E.
core +1 more source
Quantum limited amplification with a nonlinear cavity detector
, 2010 We consider the quantum measurement properties of a driven cavity with a Kerr-type nonlinearity which is used to amplify a dispersively coupled input signal.
Clerk, Aashish A., Laflamme, Catherine
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Tracking receiver Patent [PDF]
, 1967 Design and development of tracking receiver for tracking satellites and receiving radio signal transmissions under adverse noise ...
Glomb, W. L., Imboldi, E., Janeff, W.
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Insulated electrocardiographic electrodes [PDF]
, 1975 An integrated system is disclosed including an insulated electrode and an impedance transformer which can be assembled in a small plastic housing and used for the acquisition of electrocardiographic data.
David, R. M., Portnoy, W. A.
core +1 more source