The S Protein of SARS-CoV-2 Injures Cardiomyocytes Indirectly through the Release of Cytokines Instead of Direct Action. [PDF]
Acta Cardiol Sin, 2021 Chang WT, Lin YW, Chen ZC, Liu PY.
europepmc +1 more source
Toward an ecological aesthetics: music as emergence [PDF]
, 2003 In this article we intend to suggest some ecological based principles to support the possibility of develop an ecological aesthetics. We consider that an ecological aesthetics is founded in concepts as “direct perception”, “acquisition of affordances and
Oliveira, A. L. G., Oliveira, L. F.
core
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis. [PDF]
Hepatol Commun, 2022 Gluais-Dagorn P +11 more
europepmc +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Direct action self-help (DASH) groups in UK flood risk management
E3S Web of Conferences, 2016 This paper presents an analysis of the nature and effectiveness of community direct action self-help (DASH) groups and includes a case study analysis of a river conveyance management group and a sea wall management group.
Simm Jonathan
doaj +1 more source
, 1999 We identify the Grothendieck group of certain direct sum of singular blocks of the highest weight category for sl(n) with the n-th tensor power of the fundamental (two-dimensional) sl(2)-module.
Bernstein, Joseph +2 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
GENDER AND THE RIGHT TO NON-DISCRIMINATION IN INTERNATIONAL HUMAN RIGHTS LAW [PDF]
Journal of Liberty and International Affairs, 2016 Discrimination against women based on the fact that they are women is a deeply rooted practice in all societies. However, the level of discrimination varies greatly with the level of development of the given society and strongly influences and vice versa
Bistra Netkova
doaj
Cytotoxicity of snake venom Lys49 PLA2-like myotoxin on rat cardiomyocytes ex vivo does not involve a direct action on the contractile apparatus. [PDF]
Sci Rep, 2021 López-Dávila AJ +7 more
europepmc +1 more source