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Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

open access: yesAdvanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon   +6 more
wiley   +1 more source
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Allergic rhinitis: Direct and indirect costs

Allergy and Asthma Proceedings, 2010
Allergic rhinitis is one of the most common conditions affecting both children and adults. Along with the burden of the disease and decrease in quality of life associated with allergic rhinitis, there are high costs related to the disorder. Costs due to allergic rhinitis can be divided into two categories: direct costs that are related to monies spent ...
Michael S Blaiss
exaly   +3 more sources

The direct and indirect costs of axial spondyloarthritis (axSpA) in Singapore

International Journal of Rheumatic Diseases, 2020
AbstractObjectiveTo estimate the economic annual direct and indirect costs of axial spondyloarthritis (axSpA) in Singapore, and to identify factors associated with these costs.MethodsA retrospective, cross‐sectional, Institutional Review Board‐approved study was conducted.
Julian Thumboo   +2 more
exaly   +3 more sources

Rheumatoid arthritis: direct and indirect costs

Joint Bone Spine, 2004
Rheumatoid arthritis (RA) causes disability, deformities, progressive radiological joint damage often with a need for joint replacement surgery, premature death, and alterations in quality of life. The economic burden created by RA is enormous. Direct costs per patient have been estimated at 1812-11,792 Euro annually and indirect costs at 1260-37,994 ...
Anne-Christine, Rat   +1 more
openaire   +2 more sources

Direct and indirect costs of asthma to an employer

Journal of Allergy and Clinical Immunology, 2002
Asthma is a chronic inflammatory condition of the airways that has a significant effect on the use of health care resources.This study is the first of its kind to estimate the overall cost of asthma to a major employer in the United States and to profile the nature of the asthma expenses.The annual per capita cost of asthma was determined for ...
Howard G, Birnbaum   +6 more
openaire   +2 more sources

The direct and indirect costs of Dravet Syndrome

Epilepsy & Behavior, 2018
The objective of this study was to estimate the annual direct and indirect costs associated with Dravet Syndrome (DS).A survey was electronically administered to the caregivers of patients with DS treated at Children's Hospital Colorado. Survey domains included healthcare utilization of the patient with DS and DS caregiver work productivity and ...
Melanie D, Whittington   +5 more
openaire   +2 more sources

Costs of endometriosis in Austria: a survey of direct and indirect costs

Archives of Gynecology and Obstetrics, 2013
The literature includes a wealth of medical data on endometriosis, but the economic significance of the condition has so far been neglected. An analysis of hospital costs for endometriosis in Austria was, therefore, carried out for economic purposes.Seventy-three patients with endometriosis were included in the study.
Johanna, Prast   +5 more
openaire   +2 more sources

Direct and Indirect Costs of Rheumatoid Arthritis to an Employer

Journal of Occupational and Environmental Medicine, 2000
This study is among the first to estimate the overall economic burden of rheumatoid arthritis (RA) from an employer perspective. The annual, per capita cost of RA was determined for beneficiaries of a major employer by analyzing medical, pharmaceutical, and disability claims data.
H G, Birnbaum   +6 more
openaire   +2 more sources

Determinants of direct and indirect costs in anorexia nervosa

International Journal of Eating Disorders, 2014
ABSTRACTObjectiveTo estimate direct and indirect costs of anorexia nervosa (AN), and to identify cost determinants.MethodsIn a subsample (n = 225) of the ANTOP trial (Anorexia Nervosa Treatment of OutPatients) health care utilization and productivity losses were assessed at baseline for the previous 3 months and monetarily valued. Included were females
Nina, Stuhldreher   +5 more
openaire   +3 more sources

The direct and indirect costs of explosive violence

BMJ, 2009
Violent conflict remains a major risk to human health and explosive weapons are an important cause of death and injury in such situations. The health consequences are devastating. Explosive weapons cause death, injury, and psychological disabilities. They also cost lives through their effects on the health system, human resources in health, water and ...
openaire   +2 more sources

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