Results 1 to 10 of about 15,752,675 (317)

Propafenone HCl fast dissolving tablets containing subliming agent prepared by direct compression method [PDF]

open access: yesSaudi Pharmaceutical Journal, 2017
Propafenone HCl (PPH), an antiarrhythmic drug, has a bitter taste, short half-life, delayed drug dissolution and side effects. Thus, the purpose of this work is to develop orally fast dissolving tablets (OFDTs) containing PPH to provide a rapid drug ...
Saleh Abd El Rasoul, Gamal A. Shazly
doaj   +3 more sources

Effect of binder type and lubrication method on the binder efficacy for direct compression

open access: yesInternational Journal of Pharmaceutics, 2021
The effect of different binders for direct compression on tablet critical quality attributes was investigated. Dicalcium phosphate, lactose and microcrystalline cellulose were used as fillers and combined with ten binders (10, 20 and 30% w/w). Binder properties were linked to tensile strength via partial least square analysis.
Thomas De Beer   +2 more
exaly   +5 more sources

Development of Oral Tablet Formulation Containing Erlotinib: Randomly Methylated-β-cyclodextrin Inclusion Complex Using Direct Compression Method [PDF]

open access: yesTurk J Pharm Sci, 2021
Objectives Erlotinib (ERL) is a tyrosine kinase inhibitor that has been used in the treatment of metastatic non-small cell lung cancer (NSCLC). However, its low aqueous solubility limits its absorption and oral bioavailability.
Erdoğar N.
europepmc   +2 more sources

Preparation of glimepiride mucoadhesive tablets by direct compression method and their in-vitro evaluation

open access: yesJournal of Contemporary Pharmacy, 2019
Objectives: The present investigation is concerned with formulation and evaluation of mucoadhesive buccal tablets containing antidiabetic drug, glimepiride, to circumvent the first pass effect and to improve its bioavailability with reduction in dosing ...
Anum Akram, Ayesha Kiran, Saddiqa Naeem
doaj   +2 more sources

Control strategy and methods for continuous direct compression processes

open access: yesAsian Journal of Pharmaceutical Sciences, 2021
We presented a control strategy for tablet manufacturing processes based on continuous direct compression. The work was conducted by the experts of pharmaceutical companies, machine suppliers, academia, and regulatory authority in Japan.
Yasuhiro Suzuki   +16 more
doaj   +3 more sources

New Text Compression Method Based on Direct Solution Method Neural Networks

open access: yesمجلة علوم ذي قار, 2019
The aim of this work is to create a text compression technique using a single layer neural networks trained using direct solution method. In this work, the text is made as desired output and the weights are pre-defined then, by using the direct ...
Ali Hussen Hassan
doaj   +8 more sources

Formulation and evaluation of floating tablet of nimesulide by direct compression method

open access: yesMagna Scientia Advanced Research and Reviews
Nimesulide has been used versatile on fever, pain, inflammation, rheumatoid arthritis, tendinitis, thrombophlebitis and trauma. Common drawbacks of conventional tablet dosage forms of nimesulide show an irritant effect on the stomach due to its weakly acidic nature along it has short duration of action leading to poor bioavailability.
null Sanjiv Kumar Pandey   +6 more
openaire   +2 more sources

Development of co-processed excipients in the design and evaluation of atorvastatin calcium tablets by direct compression method.

open access: yesInt J Pharm Investig, 2014
Introduction: Co-processed excipients were prepared to improve the process ability and efficacy of commonly used excipients and to impart multi-functional qualities to the excipients and hence that the tablets with the desired attributes can be produced.
Pusapati RT   +3 more
europepmc   +2 more sources

Formulation Development and Optimization of Febuxostat Tablets by Direct Compression Method

open access: yesAdvances in Polymer Technology, 2015
ABSTRACTThe aim of this study was to develop a simple and cost‐effective Febuxostat film coated tablet formulation by the direct compression method. To obtain the best optimized product, nine different formulations were developed using a central composite rotatable design.
Uzma Asif   +6 more
openaire   +2 more sources

Design, Formulation and Evaluation of Physicochemical Properties of Valacyclovir Effervescent Tablet [PDF]

open access: yesTrends in Pharmaceutical Sciences, 2022
Valacyclovir (VA) displays antiviral activity against Herpes simplex virus (HSV) and Varicella zoster virus (VZV). The aim of this study was to design, formulate and evaluate the physicochemical properties of effervescent tablets containing VA in order ...
Somayeh Taymouri   +2 more
doaj   +1 more source

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