Results 111 to 120 of about 1,079,290 (315)
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
ClinicoEconomics and Outcomes Research, 2020 Addisu Bogale Zawudie, 1 Teferi Daba Lemma, 2 Dawit Wolde Daka 2 1Pathfinder International Ethiopia, Addis Ababa, Ethiopia; 2Faculty of Public Health, Department of Health Policy and Management, Jimma University, Jimma, EthiopiaCorrespondence: Dawit ...
Zawudie AB, Lemma TD, Daka DW
doaj
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
On the (ir)relevance of direct supply-side effects of monetary policy [PDF]
The relevance of direct supply-side effects of monetary policy in a New Keynesian DSGE model is studied. We extend a model with several nominal and real frictions by introducing a cost channel of monetary transmission and allowing for non-separability of
Paul Levine +3 more
core
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Heterodox production and cost theory of the business enterprise [PDF]
Heterodox economists long complained about having no systematic alternative to neoclassical production and cost theory. This paper deals with this complaint.
Lee, Frederic, Jo, Tae-Hee
core +1 more source
Annual cost of treatment for schizophrenia: Estimation from a university hospital data in Turkey
Psychiatry and Clinical Psychopharmacology, 2021 Objective: The annual cost of treatment for schizophrenia is unknown in Turkey. The goal of this study was to estimate the annual cost of treatment for schizophrenia by calculating the expenditures of schizophrenia patients treated at a university ...
Mustafa Yıldız, Cem Cerit
doaj
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source