Results 61 to 70 of about 3,265,997 (303)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
CALCULATION OF COMPANY COSTS THROUGH THE DIRECT-COSTING CALCULATION METHOD [PDF]
, 2013 The cost of production has as its starting point the purchase cost of raw materials and consumables, as well as their processing cost and the calculation of the production cost involves complex aspects.
Florin-Constantin DIMA
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, 1960 Thesis (M.B.A.)--Boston UniversityAccounting as a profession has made outstanding progress up through the mid-years of the century. Notwithstanding that it has grown from historical record-keeping to a functional position indispensable in the conduct of ...
Anderson, Ralph E.
core +1 more source
Applying Time-Driven Activity-Based Costing in the ICU Ward of Shariati Hospital of Isfahan Province [PDF]
حسابداری سلامت, 2013 Introduction: Since determining the revenues of services is based on tarrif, the factor of costs and their method of allocation are the only accessible variable to the hospital managers.
A. Khani, S. Mehrani, E. Ghane
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
METHOD TIME DRIVEN ACTIVITY BASED COSTING – LITERATURE REVIEW [PDF]
This article presents a literature review of the method Time Driven Activity Based Costing, like an instrument to better assignment of costs to activities and their comparison with antecedent method Activity Based Costing.
Oleg DEJNEGA
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ASPECTS REGARDING THE APPLICATION OF DIRECT-COSTING IN TAKING THE MANAGERIAL DECISIONS [PDF]
, 2008 Direct-costing represents a method of calculation which, although can not be used in financial reporting, represents a very strong instrument of analysis within reach of enterprise’s management. The method direct-costing requires the delimitation between
Briciu Sorin, Sas Florentina
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Calculation in direct-costing system and absorption costing system
, 2015 This article explores the essence and characteristics of the methods of cost accounting and unit costing: the full distribution of costs («absorption-costing») and the calculation according to variable costs («direct-costing»).
Осадча, Г.Г. +1 more
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