Results 51 to 60 of about 2,530,249 (265)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Citation: 'direct current' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.D01767 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
Alfredo Bermúdez +2 more
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EXPLORING STUDENTS' PROBLEM-SOLVING SKILLS ON DIRECT CURRENT ELECTRICAL IN VOCATIONAL HIGH SCHOOL
This research aimed to explore the problem-solving skills of Vocational High School in Kendari students in direct current electricity. The research used the descriptive-quantitative method, and the research sample was twelve science-grade students in ...
Luh Sukariasih +3 more
doaj +1 more source
Perinatal Carcinogenesis: Current Directions [PDF]
While perinatal animals exhibit unique sensitivity to carcinogenesis, the extent to which perinatal human exposures contribute to cancer risk remains largely unknown. Investigation of this possibility is proceeding down four general avenues: biochemical/molecular mechanisms of tumourigenesis in the perinatal period; postnatal influences on prenatally ...
L M, Anderson, A B, Jones, J M, Rice
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Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Study of the characteristics of external noise of dual-powered electric locomotive
The article presents the results of tests of a freight dual-system electric locomotive 2EV120 when operating in stationary mode and moving at normalized speed.
M. Yu. NOSKOV +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Amplification of Small Direct Currents [PDF]
A new type of thermionic tube recently described by Metcalf and Thompson has made it possible for the first time to construct d.c. amplifying circuits with a current sensitivity exceeding that of any form of electrometer except the Hoffman; and with a ruggedness and dependability unattainable with any form of sensitive electrometer.
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