Results 241 to 250 of about 3,454,909 (295)

A Strategy Potentially Suitable for Combined Preimplantation Genetic Testing of Aneuploidy and Monogenic Disease That Permits Direct Detection of Pathogenic Variants Including Repeat Expansions and Gene Deletions. [PDF]

Int J Mol Sci
Tan VJ, Liang Y, Tan AS, Wong S, Asherah N, Chua P, Lee CG, Choolani MA, Dang T, Chong SS.   +9 more
europepmc   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Evaluation of analyte-specific reagents for the direct detection of Pneumocystis jirovecii. [PDF]

J Clin Microbiol
Giffen SR, Stoeppler E, Elliott A, Miller MB.   +3 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Direct detection of the chloride release and uptake reactions of Natronomonas pharaonis halorhodopsin. [PDF]

J Biol Chem
Hamada C, Murabe K, Tsukamoto T, Kikukawa T.   +3 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Acid Cleavable Biotin-Alkyne Improves Sensitivity for Direct Detection of Biotin Labeled Peptides in Biorthogonal Noncanonical Amino Acid Tagging Analysis. [PDF]

J Proteome Res
McClatchy DB, Garrett PT, Jung T, Diedrich JK, Yates JR.   +4 more
europepmc   +1 more source

Performance of direct detection of <i>Mycobacterium tuberculosis</i> within <i>Mycobacterium tuberculosis</i> complex by routine MALDI-TOF for diagnosis using species-specific lipid fingerprint. [PDF]

Microbiol Spectr
Cheong B, He C, Laurenson I, Claxton P, Kostrzewa M, Drobniewski F, Larrouy-Maumus G.   +6 more
europepmc   +1 more source

Direct Detection of Bound Water in Hydrated Powders of Lysozyme by Differential Scanning Calorimetry. [PDF]

ACS Phys Chem Au
Peters J, Kornmueller K, Dannaoui R, Syla E, Pastore A.   +4 more
europepmc   +1 more source