Results 51 to 60 of about 7,321,963 (311)

Direct Detection and Quantification of Neoantigens [PDF]

Cancer Immunology Research, 2019
Abstract Many immunotherapeutic approaches under development rely on T-cell recognition of cancer-derived peptides bound to human leukocyte antigen molecules on the cell surface. Direct experimental demonstration that such peptides are processed and bound is currently challenging.
Qing Wang, Jacqueline Douglass, Michael S. Hwang, Emily Han-Chung Hsiue, Brian J. Mog, Ming Zhang, Nickolas Papadopoulos, Kenneth W. Kinzler, Shibin Zhou, Bert Vogelstein   +9 more
openaire   +2 more sources

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Implementation of a Reconfigurable Optical Logic Gate Using a Single I/Q Modulator With Direct Detection

IEEE Photonics Journal, 2016
We propose and investigate a new scheme to realize all-optical logic gates using a single I/Q modulator with direct detection. Both intensity and phase of the optical signal are utilized to represent the four different states of two binary inputs ...
Xianfeng Tang, Yaxue Zhai, Lu Sun, Yiqiao Feng, Donghe Zhao, Xiaoguang Zhang, Lixia Xi, Wenbo Zhang   +7 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Airborne direct-detection and coherent wind lidar measurements along the east coast of Greenland in 2009 supporting ESA’s Aeolus mission [PDF]

, 2011
The Aeolus mission of the European Space Agency (ESA) will send the first wind lidar to space to fulfill the utmost need for global wind profile observations.
Witschas, Benjamin, Uwe Marksteiner, Stephan Rahm, Reitebuch, Oliver, Marksteiner, Uwe, Rahm, Stephan, Ines Nikolaus, Benjamin Witschas, Lemmerz, Christian, Oliver Reitebuch, Nikolaus, Ines, Christian Lemmerz   +11 more
core   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Calibrations and Wind Observations of an Airborne Direct-Detection Wind LiDAR Supporting ESA’s Aeolus Mission

Remote Sensing, 2018
The Aeolus satellite mission of the European Space Agency (ESA) has brought the first wind LiDAR to space to satisfy the long-existing need for global wind profile observations.
Uwe Marksteiner, Christian Lemmerz, Oliver Lux, Stephan Rahm, Andreas Schäfler, Benjamin Witschas, Oliver Reitebuch   +6 more
doaj   +1 more source

Motion detection and directional tuning

Vision Research, 1998
A random dot pattern was presented which made two jumps in various directions with a variable delay between them. The jumps occurred at the frame transitions of a 3-frame apparent motion sequence. The variation in detectability with the directional difference and the temporal separation of the jumps allows us to make inferences about directional tuning
Simpson, William A, Newman, Aaron
openaire   +2 more sources