Results 81 to 90 of about 3,454,909 (295)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

A Reconfigurable Optical Logic Gate With up to 25 Logic Functions Based on Polarization Modulation With Direct Detection

open access: yesIEEE Photonics Journal, 2017
We propose and investigate a new scheme to realize optical logic gates using polarization addition with direct detection. Two polarizations of an optical signal are modulated, respectively, by independent binary inputs to represent four different states,
Xianfeng Tang   +8 more
doaj   +1 more source

Neutrino Indirect Detection of Neutralino Dark Matter in the CMSSM

open access: yes, 2002
We study potential signals of neutralino dark matter indirect detection by neutrino telescopes in a wide range of CMSSM parameters. We also compare with direct detection potential signals taking into account in both cases present and future experiment ...
Bertin, V., Nezri, E., Orloff, J.
core   +2 more sources

Leptophilic Dark Matter with $Z'$ interactions [PDF]

open access: yes, 2014
We consider a scenario where dark matter (DM) interacts exclusively with Standard Model (SM) leptons at tree level. Due to the absence of tree-level couplings to quarks, the constraints on leptophilic dark matter arising from direct detection and hadron ...
Bell, Nicole F.   +3 more
core   +2 more sources

DIRECTIONAL DETECTION OF DARK MATTER [PDF]

open access: yesModern Physics Letters A, 2009
Direct detection of WIMPs is key to understand the origin and composition of Dark Matter. Among the many experimental techniques available, those providing directional information have the potential of yielding an unambiguous observation of WIMPs even in the presence of insidious backgrounds.
openaire   +2 more sources

Scalar direct detection: In-medium effects

open access: yesPhysics Letters B, 2020
A simple extension of the Standard Model consists of a scalar field that can potentially constitute the dark matter (DM). Significant attention has been devoted to probing light $\mathcal{O}(\lesssim 10~\rm{eV})$ scalar DM, with a multitude of experimental proposals based on condensed matter systems as well as novel materials.
Gelmini G. B.   +2 more
openaire   +5 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Supersymmetric Dark Matter Detection at Post-LEP Benchmark Points [PDF]

open access: yes, 2001
We review the prospects for discovering supersymmetric dark matter in a recently proposed set of post-LEP supersymmetric benchmark scenarios. We consider direct detection through spin-independent nuclear scattering, as well as indirect detection through ...
Ellis, John   +4 more
core   +1 more source

Direct Detection of Non-Chiral Dark Matter

open access: yes, 2009
Direct detection experiments rule out fermion dark matter that is a chiral representation of the electroweak gauge group. Non-chiral real, complex and singlet representations, however, provide viable fermion dark matter candidates.
P. L. Brink, R. Bernabei, Rouven Essig
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel   +3 more
wiley   +1 more source

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