Results 81 to 90 of about 6,580,241 (312)
Creating grippers that can perform tasks similar to a human hand's capability is a challenge yet to be solved. Most electrical actuators used in grippers have been geared, working at high numbers of revolutions per minute. By being geared, the motor can achieve high precision and efficiency in repetitive tasks.
openaire +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Current Status and Trend of Motor Direct-Drive Technology of Electric Rigs
Insufficient reliability of conventional drilling equipment and increasingly stringent energy-saving environmental protection requirements restraint the increase of drilling efficiency.
Wei Chao, Zhou Sizhu, Li Meiqiu
doaj
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
AUTOMATED SEWING WITH DIRECT DRIVE MANIPULATOR
Abstract A 3-D automated sewing system with a 6 DOF direct drive manipulator is introduced to improve productivity and to promote automation in the apparel industries. A smooth trace technique is adopted by improving the conventional position/force hybrid control method to attain high sewing accuracy as well as to eliminate burdensome motion teaching.
T. Arai, T. Nakamura, M. Sato
openaire +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This study focuses on the optimization of beam chamber geometry designs for future direct-drive laser facilities. It provides a review of leading target chamber geometries, with a particular emphasis on random errors.
D. Viala +3 more
doaj +1 more source

