Results 251 to 260 of about 9,120,926 (345)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dexamethasone treatment influences tendon healing through altered resolution and a direct effect on tendon cells. [PDF]

Sci Rep
Dietrich-Zagonel F, Alim MA, Beckman LB, Eliasson P.   +3 more
europepmc   +1 more source

The importance of foreign direct investments and their effect on agriculture and food industry in Serbia.

, 2008
R. Jovanović
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Author Correction: The direct effect of SARS-CoV-2 virus vaccination on human ovarian granulosa cells explains menstrual irregularities. [PDF]

NPJ Vaccines
Bar-Joseph H, Raz Y, Eldar-Boock A, Michaan N, Angel Y, Saiag E, Nemerovsky L, Ben-Ami I, Shalgi R, Grisaru D.   +9 more
europepmc   +1 more source

Controlled direct effect of psychiatric disorders on cardiovascular disease: evidence from a large Kurdish cohort. [PDF]

BMC Cardiovasc Disord, 2020
Darabi Z, Najafi F, Safari-Faramani R, Salimi Y.   +3 more
europepmc   +1 more source

1511 Effect of Copper Wire Location and Voids on Evaluation of Interface Crack between Solder Ball and Copper by Direct Current Potential Difference Method

, 2009
Ryoichi Nakahara, Naoto Yoshida, Naoya TADA   +2 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

The direct effect of SARS-CoV-2 virus vaccination on human ovarian granulosa cells explains menstrual irregularities. [PDF]

NPJ Vaccines
Bar-Joseph H, Raz Y, Eldar-Boock A, Michaan N, Angel Y, Saiag E, Nemerovsky L, Ben-Ami I, Shalgi R, Grisaru D.   +9 more
europepmc   +1 more source

Site-directed mutation of a laccase from Thermus thermophilus: Effect on the activity profile

, 2012
Xin Liu, Meng Tian, Liu Ke-wu
openalex   +2 more sources