Results 101 to 110 of about 1,407,780 (327)

Phase transitions and dynamical properties of quasi-one-dimensional structures with hydrogen bonds [PDF]

, 2012
The frequency dependence of dynamical conductivity of the quasi-one-dimensional structures with hydrogen bonds is studied on the basis of pseudospin-electron model. It takes into account the proton-electron interaction, external longitudinal field h, the
Stetsiv, R. Ya.
core   +5 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Electrochemical performance and microbial community profiles in microbial fuel cells in relation to electron transfer mechanisms

BMC Microbiology, 2017
Background Microbial fuel cells (MFCs) operating with complex microbial communities have been extensively reported in the past, and are commonly used in applications such as wastewater treatment, bioremediation or in-situ powering of environmental ...
Naroa Uria, Isabel Ferrera, Jordi Mas
doaj   +1 more source

Bioconversion of CO to formate by artificially designed carbon monoxide:formate oxidoreductase in hyperthermophilic archaea

Communications Biology, 2022
Synthetic carbon monoxide:formate oxidoreductase is designed for direct electron transfer between non-interacting CO dehydrogenase and formate dehydrogenase using an electron-transferring Fe-S fusion protein in T. onnurineus.
Jae Kyu Lim, Ji-In Yang, Yun Jae Kim, Yeong-Jun Park, Yong Hwan Kim   +4 more
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Direct Electron Transfer of Myoglobin on CdO Nanoparticles Modified Glassy Carbon Electrode

International Journal of Electrochemical Science, 2013
In this study, direct electron transfer of myoglobin (Mb) on cadmium oxide (CdO) nanoparticles modified glassy carbon electrode (GCE) was investigated. Prepared CdO nanoparticles were studied by X-Ray diffraction (XRD) and UV–visible absorption methods ...
Nooshin Mohammadi, Yousoof Ghanbari-kakavandi, Ali Akbar Movassagh, Somayeh Nasereslami, Gholamreza Mohseni, Abbas Hajiosseinlo, Leila Sofimaryo, Reza Soleimani, Hajar Akbari-dastjerdi, Masoud Negahdary   +9 more
doaj   +1 more source

Nanoporous gold based electrodes for electrochemical studies of human neuroglobin

Electrochemistry Communications, 2020
Human neuroglobin (Ngb) is a heme protein expressed in the brain tissue and retina with an important neuroprotective role. However, its molecular mechanism is still under exploration.
Yasuhiro Mie, Kyoka Takahashi, Yuka Itoga, Kenta Sueyoshi, Hirofumi Tsujino, Taku Yamashita, Tadayuki Uno   +6 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Plugging in or Going Wireless:Strategies for Interspecies Electron Transfer [PDF]

, 2014
Interspecies exchange of electrons enables a diversity of microbial communities to gain energy from reactions that no one microbe can catalyze. The first recognized strategies for interspecies electron transfer were those that relied on chemical ...
Rotaru, Amelia-Elena, Shrestha, Pravin
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source