Results 111 to 120 of about 1,407,780 (327)
An Explicit Electron-Vibron Model for Olfactory Inelastic Electron Transfer Spectroscopy
, 2019 The vibrational theory of olfaction was posited to explain subtle effects in the sense of smell inexplicable by models in which molecular structure alone determines an odorant's smell.
Blair, Enrique P., Liza, Nishattasnim
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
ElectrochemistryDirect electron transfer (DET)-type bioelectrocatalysis, in which enzymatic reactions proceed without the involvement of redox mediators, is a powerful approach for investigating intrinsic enzymatic features relevant to the development of advanced ...
Keisei SOWA
doaj +1 more source
Laser Pulse Deposited Nanosized Ceria for Direct Electron Transfer of Glucose Oxidase
International Journal of Electrochemical Science, 2014 Ceria has a high isoelectric point (IEP~9.2) and its cerium atom reversibly undergoes oxidation/reduction process therefore theoretically capable through electrostatic interactions of immobilizing enzymes with lower IEP and of electrons mediating ...
Mouna Moumene +4 more
doaj +1 more source
Optical orientation of electron spins and valence band spectroscopy in germanium
, 2015 We have investigated optical orientation in the vicinity of the direct gap of bulk germanium. The electron spin polarization is studied via polarization-resolved photoluminescence excitation spectroscopy unfolding the interplay between doping and ...
Amand, Thierry +4 more
core +1 more source
Direct simulation of proton-coupled electron transfer across multiple regimes [PDF]
, 2013 The coupled transfer of electrons and protons is a central feature of biological and molecular catalysis, yet fundamental aspects of these reactions remain poorly understood.
Kretchmer, Joshua S. +1 more
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Water Science and TechnologyUsing a batch thermophilic anaerobic system established with 60 mL serum bottles, the mechanism on how microbial enrichments obtained from magnetite-amended paddy soil via repeated batch cultivation affected methane production from acetate was ...
Zi-Fan Wu +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Importance of charge capture in interphase regions during readout of charge-coupled devices [PDF]
, 2018 The current understanding of charge transfer dynamics in charge-coupled devices (CCDs) is that charge is moved so quickly from one phase to the next in a clocking sequence and with a density so low that trapping of charge in the interphase regions is ...
Bush, Nathan +5 more
core +3 more sources