Results 81 to 90 of about 635,694 (348)

New methods for chicken embryo manipulations [PDF]

, 2010
The capacity to image a growing embryo while simultaneously studying the developmental function of specific molecules provides invaluable information on embryogenesis.
De Bellard, Maria Elena, El-Ghali, Nissrine, Ezin, Akouavi M., Rabadi, Maes   +3 more
core   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Predictive Value of Serum Antibodies and Point Mutations of AQP4, AQP1 and MOG in A Cohort of Spanish Patients with Neuromyelitis Optica Spectrum Disorders [PDF]

, 2019
The detection of IgG aquaporin-4 antibodies in the serum of patients with Neuromyelitis optica (NMO) has dramatically improved the diagnosis of this disease and its distinction from multiple sclerosis.
Abril-Jaramillo, Javier, Casado Chocán, José Luis, Díaz Sánchez, María, Echevarría Irusta, Miriam, García Miranda, Pablo, García Sánchez, María Isabel, Lamas-Pérez, Lucía, Lebrato-Hernández, Lucía, Martínez Olivo, María del Mar, Morón Civanto, Francisco Jesús, Navarro, Gemma, Ramírez Lorca, Reposo, Romera, Mercedes, Suárez-Luna, Nela, Uclés Sánchez, Antonio José   +14 more
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Rabies in Callithrix sp. in the urban area of Niterói, Rio de Janeiro, Brazil

Revista da Sociedade Brasileira de Medicina Tropical, 2020
In Brazil, rabies occurs mainly within an urban cycle, in which dogs and bats are reservoirs. This paper aims to report the occurrence of rabies in Callithrix sp. in Niterói, Rio de Janeiro, Brazil.
Flavio Fernando Batista Moutinho, Marcela Garcia Araújo de Andrade, Viviane Moura Azevedo Nunes, Eduardo Cárdenas Nogueira Rubião, Helena Beatriz de Carvalho Ruthner Batista, Phyllis Catharina Romijn, Carlos Alberto Cattaneo, Fernando Guilherme de Oliveira, Rafael de Novaes Oliveira, Nairedisa Marcanth, Leilane Gorga Gaspar Ruas Silvestre, Fábio Villas Boas Borges, Sávio Freire Bruno   +12 more
doaj   +1 more source

Campylobacteriosis in beef cattle in Alentejo – preliminary assessment [PDF]

, 2014
The aim of this study was to assess the prevalence of infection by Campylobacter fetus in beef cattle reared in extensive systems in Alentejo region by direct fluorescent antibody test (DFAT), a technique widely used for determining the prevalence of ...
Pinto Coelho, M, Potes, M.E., Queiroga, M. C.   +2 more
core  

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Comparison of biotinylated monoclonal and polyclonal antibodies in an evaluation of a direct rapid immunohistochemical test for the routine diagnosis of rabies in southern Africa.

PLoS Neglected Tropical Diseases, 2014
The major etiological agent of rabies, rabies virus (RABV), accounts for tens of thousands of human deaths per annum. The majority of these deaths are associated with rabies cycles in dogs in resource-limited countries of Africa and Asia.
Andre Coetzer, Claude T Sabeta, Wanda Markotter, Charles E Rupprecht, Louis H Nel   +4 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Rapid detection of Pneumocystis carinii using a direct fluorescent monoclonal antibody stain [PDF]

Journal of Clinical Microbiology, 1990
A collaborative study was undertaken at two institutions to assess the performance of a direct fluorescent-antibody stain for the detection of Pneumocystis carinii in respiratory specimens from patients with known or suspected human immunodeficiency virus type 1 infections.
N Rollins, D M Yajko, Valerie L. Ng, M Krieger, R E Chaisson, H T Sphar, N A Virani, W K Hadley, P Charache, K Cabrian   +9 more
openaire   +3 more sources