Results 171 to 180 of about 2,076,692 (292)

Direct Imaging of Lipid Metabolic Changes in <i>Drosophila</i> Ovary During Aging Using DO-SRS Microscopy. [PDF]

Front Aging, 2021
Li Y, Bagheri P, Chang P, Zeng A, Hao J, Fung A, Wu JY, Shi L.   +7 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Direct Imaging and Location of Pb²⁺ and K⁺ in EMT Framework-Type Zeolite. [PDF]

J Phys Chem C Nanomater Interfaces, 2021
Zhang Y, Smith D, Readman JE, Mayoral A.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Neural Network-Based Study for Rice Leaf Disease Recognition and Classification: A Comparative Analysis Between Feature-Based Model and Direct Imaging Model. [PDF]

Food Sci Nutr
Prity FS, Raquib M, Murad SA, Rafi MJ, Bhuiyan MK, Bairagi AK.   +5 more
europepmc   +1 more source

Direct Imaging of Plant Metabolites in the Rhizosphere Using Laser Desorption Ionization Ultra-High Resolution Mass Spectrometry. [PDF]

Front Plant Sci, 2021
Lohse M, Haag R, Lippold E, Vetterlein D, Reemtsma T, Lechtenfeld OJ.   +5 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Direct imaging of pulmonary gas exchange with hyperpolarized xenon MRI. [PDF]

Innovation (Camb)
Li H, Li H, Zhang M, Huang C, Zhou X.
europepmc   +1 more source

A method for direct imaging of x-z cross-sections of fluorescent samples. [PDF]

J Microsc, 2021
Katiyar A, Antani JD, McKee BP, Gupta R, Lele PP, Lele TP.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source