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FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
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Intervention in School and Clinic, 1998
This article outlines the underlying instructional design principles that are at the heart of the Direct Instruction Model and illustrates the application of those principles to a variety of content areas. The authors provide a rationale for the integration of curriculum design principles with effective teaching practices along with criteria for ...
Marcy Stein +2 more
openaire +1 more source
This article outlines the underlying instructional design principles that are at the heart of the Direct Instruction Model and illustrates the application of those principles to a variety of content areas. The authors provide a rationale for the integration of curriculum design principles with effective teaching practices along with criteria for ...
Marcy Stein +2 more
openaire +1 more source
School Psychology International, 1990
Direct instruction approaches to the teaching of English spelling skills are described and evaluated. Two commercially available direct instruction spelling programmes (Spelling Mastery and Corrective Spelling through Morphographs) are outlined. Two Hong Kong projects utilizing these programmes are described; one in a primary school and the other in a
Sam Winter +2 more
openaire +1 more source
Direct instruction approaches to the teaching of English spelling skills are described and evaluated. Two commercially available direct instruction spelling programmes (Spelling Mastery and Corrective Spelling through Morphographs) are outlined. Two Hong Kong projects utilizing these programmes are described; one in a primary school and the other in a
Sam Winter +2 more
openaire +1 more source
Direct Instruction: a model of instructional design
Educational Psychology, 1986Abstract Instructional design is chiefly concerned with the arrangement of the environment to optimise learning according to various criteria. While there are a number of instructional design theories and models, the Direct Instruction Model (Engelmann & Carnine, 1982) is the focus of this paper.
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Danger of "as directed" instructions
American Journal of Health-System Pharmacy, 2001J, Sitowitz, S B, Roberts
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Let's talk evidence – The case for combining inquiry-based and direct instruction
Educational Research Review, 2023Ton de Jong +2 more
exaly