Results 151 to 160 of about 11,112,016 (340)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Total direct health provider costs by discharge medical diagnosis (n = 647).

, 2018
Total direct health provider costs by discharge medical diagnosis (n = 647).
Peter MacPherson (2827067), Hendramoorthy Maheswaran (186758), Danielle Cohen (4966297), Stavros Petrou (3468155), Elizabeth L. Corbett (232781), David G. Lalloo (101770), Aileen Clarke (470453), Felistas Kumwenda (3549965)   +7 more
core   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Annual Direct Medical Costs for Diabetes-Related Complications (2014 Chinese Yuan).

, 2016
Annual Direct Medical Costs for Diabetes-Related Complications (2014 Chinese Yuan).
Hengjin Dong (398458), Shuyan Gu (736892), Xiaoqian Hu (556383), Demin Yu (3359162), Yuhang Zeng (3328578)   +4 more
core   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Standard of care and direct medical costs of the treatment of chronic lymphocytic leukemia among the adult population in Ukraine, Russia, and Kazakhstan: data from the LEUKOSPECT study

, 2017
Averyan Vasylyev,1 Valentina Molostvova,2 Boris A Rebrov,3 Janina Makarova,4 Andrey Zaritskey,5 Vadim Ptushkin,6 Raigul Ramazanova,7 Yuriy Popovych,8 Orest Tsyapka,9 Evgeny Pashanov10 1CIS Medical, GlaxoSmithKline, Kiev, Ukraine; 2Regional Clinical ...
Zaritskey A, Popovych Y, Pashanov E, Vasylyev A, Makarova J, Ptushkin V, Molostvova V, Rebrov BA, Ramazanova R, Tsyapka O   +9 more
core  

Index-hospitalization direct medical Costs between CRC patients who underwent two surgical approaches.

, 2019
Index-hospitalization direct medical Costs between CRC patients who underwent two surgical approaches.
Jaw-Yuan Wang (184150), Herng-Chia Chiu (336309), Hui-Min Hsieh (570112), Chi-Lin Wan (6191462), Hsiang-Lin Tsai (428295)   +4 more
core   +1 more source

Direct Medical Costs of Diabetes and the Foot Ulcer Outpatients in A General Hospital, Yogyakarta

Jurnal Manajemen dan Pelayanan Farmasi
Background: In addition to the financial burden that Diabetes Mellitus (DM) places on diabetics and their families due to the complications of Diabetic Foot Ulcers (DFU), treatment costs are escalating.
Eka Kartika Untari, Tri Murti Andayani, Nanang Munif Yasin, Rizka Humardewayanti Asdie   +3 more
doaj   +1 more source