Results 71 to 80 of about 1,449,442 (348)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

One-year direct and indirect costs of ischaemic stroke in China

Stroke and Vascular Neurology
Background This is the first real-world study to estimate the direct costs and indirect costs of first-ever ischaemic stroke with 1-year follow-up in China, based on a nationally representative sample.Methods Patients were chosen from 20 geographically ...
Yongjun Wang, Jing Jing, Hao Li, Xia Meng, Anxin Wang, Yong Jiang, Jinxi Lin, Qin Xu, Wei Lv, Qianyi Wang, Yi Han, Ruimin Wang, Shuqing Wu   +12 more
doaj   +1 more source

The health care burden and societal impact of acute otitis media in seven European countries: results of an Internet survey [PDF]

, 2010
This paper estimates medical resource use, direct costs, and productivity losses and costs (indirect costs) during episodes of acute otitis media (AOM) in young children.
Brosa, M. (Max), Francois, M. (Martine), Gasparini, R. (Roberto), Stolk, E.A. (Elly), Wolleswinkel-van den Bosch, J.H. (Judith)   +4 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

The Cost of Von Willebrand Disease in Europe: The CVESS Study

Clinical and Applied Thrombosis/Hemostasis, 2022
Background Von Willebrand disease (VWD) is one of the most common inherited bleeding disorders, imposing a substantial health impact and financial burden.
George Morgan MSc, Sarah Brighton BSc, Mike Laffan BA, BMBCh, DM, FRCP, FRCPath, Jenny Goudemand MD, Bethany Franks MSc, Alan Finnegan PhD, RN, FRCN, FRSA, CF, FAAN   +5 more
doaj   +1 more source

Inclusion of Persons with Disabilities in the Health Financing System in Tanzania [PDF]

, 2013
This report assesses the potential barriers and obstacles that people with disabilities might face when accessing health care services. It is the overall objective of this study to provide evidence on obstacles and financial barriers that people with ...
Ifakara Health Institute, (IHI)
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

The comparative effectiveness and cost-effectiveness of ranibizumab for neovascular macular degeneration revisited [PDF]

, 2017
BACKGROUND: To compare a near decade of follow-up, newer control cohort data, use of both the societal and third party insurer cost perspectives, and integration of unilateral/bilateral therapy on the comparative effectiveness and cost-effectiveness of ...
Adam Turpcu, Gary C. Brown, Heidi B. Lieske, Melissa M. Brown, Yamina Rajput   +4 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Medical and non-medical direct costs of cancers in patients hospitalized in Imam Khomeini cancer institution - 2010

بیمارستان, 2012
Background: With more than 12 million new cases of cancers and nearly 7.6 million deaths all around the world in 2007, cancer currently is the third leading cause of death in the world. This study was conducted to determine medical and non-medical direct
M Bazyar, A pourreza, Iraj harirchi, F Akbari, M Mahmoudi   +4 more
doaj