Results 31 to 40 of about 483 (214)
Gen-Z memory pool system implementation and performance measurement
ETRI Journal, 2022 The Gen-Z protocol is a memory semantic protocol between the memory and CPU used in computer architectures with large memory pools. This study presents the implementation of the Gen-Z hardware system configured using Gen-Z specification 1.0 and reports ...
Won-ok Kwon +4 more
doaj +1 more source
Моделирование и анализ информационных систем, 2022 The paper analyzes the possibilities of transforming C programming language constructs into objects of EO programming language. The key challenge of the method is the transpilation from a system programming language into a language of a higher level of ...
Alexander I. Legalov +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
AIP Advances, 2019 We measured X-ray absorption spectra of amorphous alumina with vacancy-type oxygen defects (AlOx) which exhibits the resistance random access memory (ReRAM) effect. We were able to detect changes in the electronic structure owing to the ReRAM effect.
Masato Kubota +3 more
doaj +1 more source
Impaired episodic simulation in a patient with visual memory deficit amnesia
Brain and Neuroscience Advances, 2020 For the first time, we assess episodic simulation in a patient with visual memory deficit amnesia, following damage to visual association cortices. Compared to control participants, the patient with visual memory deficit amnesia shows severely restricted
Alexander Easton +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Optimizing distributed systems with remote direct memory access
大数据, 2018 Fast network devices with RDMA support have been price-compatible with traditional network primitives such as Ethernet,and it’s now widely deployed in modern data centers.RDMA can be used in two ways.Firstly,it can optimize the messaging primitive in ...
Xingda WEI, Rong CHEN, Haibo CHEN
doaj
Evaluation of HPC Acceleration and Interconnect Technologies for High-Throughput Data Acquisition
Sensors, 2021 Efficient data movement in multi-node systems is a crucial issue at the crossroads of scientific computing, big data, and high-performance computing, impacting demanding data acquisition applications from high-energy physics to astronomy, where dedicated
Alessandro Cilardo
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source