Results 61 to 70 of about 1,699,422 (313)

Sleep directly following learning benefits consolidation of spatial associative memory [PDF]

open access: yes, 2008
Contains fulltext : 128176.pdf (publisher's version ) (Open Access)The last decade has brought forth convincing evidence for a role of sleep in non-declarative memory.
Jensen, O.   +3 more
core   +3 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Care priorities for stroke patients developing cognitive difficulties: a Delphi survey of UK professional views

open access: yesBMC Health Services Research, 2020
Background Post stroke cognitive difficulties are common but generally prioritised below other impairments. In the UK, clinical guidelines recommend a holistic review at six-months post-stroke including an assessment of cognitive function.
Eugene Y. H. Tang   +5 more
doaj   +1 more source

DRAGON: Breaking GPU Memory Capacity Limits with Direct NVM Access

open access: yesInternational Conference for High Performance Computing, Networking, Storage and Analysis, 2018
Heterogeneous computing with accelerators is growing in importance in high performance computing (HPC). Recently, application datasets have expanded beyond the memory capacity of these accelerators, and often beyond the capacity of their hosts. Meanwhile,
Pak Markthub   +4 more
semanticscholar   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Low Power Design Techniques And Its Implementation On Direct Memory Access (DMA) [PDF]

open access: yes, 2012
As the number of transistors in a SoC has been increasing rapidly, the integration complexity has increased as well. Besides complexity, IC designers also faced some other challenges including maintaining the power, performance and area of an IC ...
Shabagran, Gandi
core  

Efficient hardware architecture for fast IP address lookup [PDF]

open access: yes, 2002
A multigigabit IP router may receive several millions packets per second from each input link. For each packet, the router needs to find the longest matching prefix in the forwarding table in order to determine the packet's next-hop.
Chan, KS   +4 more
core   +1 more source

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