Results 61 to 70 of about 1,840,164 (310)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

DRAGON: Breaking GPU Memory Capacity Limits with Direct NVM Access

open access: yesInternational Conference for High Performance Computing, Networking, Storage and Analysis, 2018
Heterogeneous computing with accelerators is growing in importance in high performance computing (HPC). Recently, application datasets have expanded beyond the memory capacity of these accelerators, and often beyond the capacity of their hosts. Meanwhile,
Pak Markthub   +4 more
semanticscholar   +1 more source

Effects of transcranial direct current stimulation over left dorsolateral pFC on the attentional blink depend on individual baseline performance [PDF]

open access: yes, 2015
Selection mechanisms that dynamically gate only relevant perceptual information for further processing and sustained representation in working memory are critical for goal-directed behavior.
London, Raquel, Slagter, HA
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Minimum BER Receiver Filters with Block Memory for Uplink DS-CDMA Systems

open access: yesEURASIP Journal on Wireless Communications and Networking, 2008
The problem of synchronous multiuser receiver design in the case of direct-sequence single-antenna code division multiple access (DS-CDMA) uplink networks is studied over frequency selective fading channels.
Mérouane Debbah   +1 more
doaj   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Direct observation of electronic structure change by resistance random access memory effect in amorphous alumina

open access: yesAIP Advances, 2019
We measured X-ray absorption spectra of amorphous alumina with vacancy-type oxygen defects (AlOx) which exhibits the resistance random access memory (ReRAM) effect. We were able to detect changes in the electronic structure owing to the ReRAM effect.
Masato Kubota   +3 more
doaj   +1 more source

Care priorities for stroke patients developing cognitive difficulties: a Delphi survey of UK professional views

open access: yesBMC Health Services Research, 2020
Background Post stroke cognitive difficulties are common but generally prioritised below other impairments. In the UK, clinical guidelines recommend a holistic review at six-months post-stroke including an assessment of cognitive function.
Eugene Y. H. Tang   +5 more
doaj   +1 more source

Low Power Design Techniques And Its Implementation On Direct Memory Access (DMA) [PDF]

open access: yes, 2012
As the number of transistors in a SoC has been increasing rapidly, the integration complexity has increased as well. Besides complexity, IC designers also faced some other challenges including maintaining the power, performance and area of an IC ...
Shabagran, Gandi
core  

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