Results 61 to 70 of about 320,911 (294)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A High-Speed Dynamic Partial Reconfiguration Controller Using Direct Memory Access Through a Multiport Memory Controller and Overclocking with Active Feedback

International Journal of Reconfigurable Computing, 2011
Dynamically reconfigurable computing platforms provide promising methods for dynamic management of hardware resources, power, and performance. Yet, progress in dynamically reconfigurable computing is fundamentally limited by the reconfiguration time ...
John C. Hoffman, Marios S. Pattichis
doaj   +1 more source

Social interaction, team tacit knowledge and transactive memory: empirical support for the agile approach [PDF]

, 2012
The agile principles of social interaction and tacit knowledge were examined in this survey study of 48 software development teams. It was proposed that that team tacit knowledge is created through frequency and quality of social interactions and through
O'Connor, Rory, Ryan, Sharon, Ryan, Sharon M., Sharon Ryan (9979046), O\u27Connor, Rory V., Rory V. O'Connor (12588769)   +5 more
core  

Improving graphics processing unit performance based on neural network direct memory access controller

, 2023
In this paper proposes the design and implementation of the back propagation algorithm based neural network DMA (Direct Memory Access) Controller for use of multimedia applications.
Yatnalli, Veeramma, Bhusare, Saroja, Neelappa, Neelappa, Kumar, Santosh   +3 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Interference in Language Processing Reflects Direct-Access Memory Retrieval:Evidence from Drift-Diffusion Modeling [PDF]

, 2019
Many studies on memory retrieval in language processing haveidentified similarity-based interference as a key determinant ofcomprehension. The broad consensus is that similarity-basedinterference reflects erroneous retrieval of a non-target itemthat ...
An, Adam, Parker, Dan
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Status-Byte-Assisted RDMA Transmission Mechanism for Optimizing Multi-Task Video Streaming in Edge Computing

Applied Sciences
In the context of the rapid development of edge computing, optimizing data transmission and reducing latency is crucial for efficient collaborative processing among edge servers.
Donglei Xiao, Huiyue Yi, Wuxiong Zhang, Wenhui Shen   +3 more
doaj   +1 more source

Software-Based Self-Test of Set-Associative Cache Memories [PDF]

, 2011
Embedded microprocessor cache memories suffer from limited observability and controllability creating problems during in-system tests. This paper presents a procedure to transform traditional march tests into software-based self-test programs for set ...
Stefano Di Carlo, Alessandro Savino, Paolo Prinetto, Prinetto, Paolo Ernesto, Di Carlo, Stefano, Savino, Alessandro   +5 more
core   +1 more source