Results 191 to 200 of about 8,273,193 (339)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

An Optimal Transport Medium for SARS-CoV-2 Detection in the Direct Method of Rapid Microfluidic PCR System. [PDF]

Yonago Acta Med
Takata M, Nakamoto M, Kitaura T, Okada K, Endou H, Ma'arif AS, Nishikawa Y, Mukuda K, Morishita S, Murota H, Yamasaki A, Kageyama S, Burioka N, Chikumi H.   +13 more
europepmc   +1 more source

A direct method for the N-tetraalkylation of azamacrocycles. [PDF]

Beilstein J Org Chem, 2016
Counsell AJ, Jones AT, Todd MH, Rutledge PJ.   +3 more
europepmc   +1 more source

An Efficient Method for the Preparation of Styrene Derivatives via Rh(III)-Catalyzed Direct C–H Vinylation

, 2015
Kate D. Otley, Jonathan A. Ellman
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Finding a Direct Method for a Dynamic Process: The DD (Direct and Dynamic) Cell-Tox Method. [PDF]

Int J Mol Sci
Madorran E, Kocbek Šaherl L, Rakuša M, Takač I, Munda M.   +4 more
europepmc   +1 more source

A direct method for e-cigarette aerosol sample collection. [PDF]

Environ Res, 2016
Olmedo P, Navas-Acien A, Hess C, Jarmul S, Rule A.   +4 more
europepmc   +1 more source

New methods for describing and assessing direct speech communication under disturbing conditions

, 1990
H. Lazarus
openalex   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

A Direct Method for Determining Toricity Ratios of Toric Intraocular Lens Calculators. [PDF]

Sci Rep, 2018
Gabra LG, Sayegh SI.
europepmc   +1 more source