Results 201 to 210 of about 8,273,193 (339)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

General and Direct Method for Preparing Oligonucleotide-Functionalized Metal-Organic Framework Nanoparticles. [PDF]

J Am Chem Soc, 2017
Wang S, McGuirk CM, Ross MB, Wang S, Chen P, Xing H, Liu Y, Mirkin CA.   +7 more
europepmc   +1 more source

The direct integral method for confidence intervals for the ratio of two location parameters

, 2015
Yanqing Wang, Suojin Wang, Raymond J. Carroll   +2 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Valores de colesterol LDL en una población adulta de referencia

Medisan
Se llevó a cabo un estudio descriptivo de 205 usuarios del Laboratorio Central del Hospital Provincial Docente Clinicoquirúrgico "Saturnino Lora Torres" de Santiago de Cuba, desde diciembre del 2013 hasta igual periodo del 2014, a fin de determinar los ...
Karima Maricel Gondres Legró, Jorge Calá Fernández, Lázaro Ibrahim Romero García, Yordanys Paez Candelaria, Soraya Rodríguez Borgesç   +4 more
doaj  

Platelet Counts in Insoluble Platelet-Rich Fibrin Clots: A Direct Method for Accurate Determination. [PDF]

Front Bioeng Biotechnol, 2018
Kitamura Y, Watanabe T, Nakamura M, Isobe K, Kawabata H, Uematsu K, Okuda K, Nakata K, Tanaka T, Kawase T.   +9 more
europepmc   +1 more source

Characteristics and Health Service Utilization in Two Samples of Young Injection Drug Users Recruited Using Direct and Referral Methods in San Francisco, California

, 2013
Anne Morris, Jennifer L. Evans, F. Lucy Raymond   +2 more
openalex   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Differential Variance Analysis: a direct method to quantify and visualize dynamic heterogeneities. [PDF]

Sci Rep, 2017
Pastore R, Pesce G, Caggioni M.
europepmc   +1 more source

Determination of urinary manganese by the direct chelation-extraction method and flameless atomic absorption spectrophotometry. [PDF]

, 1978
Tsutomu Watanabe, Rikio Tokunaga, T. Iwahana, M. Tati, Masahiko Ikeda   +4 more
openalex   +1 more source