Results 161 to 170 of about 21,516,320 (280)

A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham, Casey Vanderlip, Colin Birkenbihl, Eashwar Krishna, Chizobam Ugboaja, Andrew E. Budson, Brandon Frank, for the Alzheimer's Disease Neuroimaging Initiative   +7 more
wiley   +1 more source

Disease Burden and Cost of Illness of Female Breast Cancer in Poland: A Societal-Perspective Analysis with Cost Attribution to Payers, Patients, and the Economy. [PDF]

Healthcare (Basel)
Seweryn M, Leszczyńska A, Budasz-Świderska M, Banaś T, Turek A, Potocki PM.   +5 more
europepmc   +1 more source

Improving the Diagnostic Accuracy of Plasma Alzheimer's Disease Biomarkers With Objective and Subjective Cognitive Screening

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Blood‐based biomarkers are increasingly used to identify Alzheimer's disease (AD) pathology and may play an important role in early disease screening and participant selection for clinical trials. However, their performance across stages of cognitive impairment remains unclear. This study examined whether plasma biomarkers differ in
Maryam Abdolmaleki, Leslie S. Gaynor, Dandan Liu, Timothy J. Hohman, Katherine A. Gifford, Henrik Zetterberg, Angela L. Jefferson, Corey J. Bolton   +7 more
wiley   +1 more source

A Cost-of-illness Study on The Economic Burden of Breast Cancer in Turkiye: A Delphi Panel-based Analysis of Direct and Indirect Costs

OBJECTIVE To determine the economic burden of breast cancer in Turkiye. METHODS In this cost-of-illness study, per-patient annual direct and indirect medical costs for the management of breast cancer (in newly diagnosed and former patients and in ...
AKYÜREK, NALAN, Oksuzoglu, Berna, Bilici, Ahmet, Ergin, Ozge, Karabulut, Bulent, Geredeli, Caglayan, Demirci, Umut, Sar, Cigdem, Karadurmus, Nuri, Malhan, Simten, Akinci, Muhammed Bulent, Sendur, Mehmet Ali   +11 more
core   +1 more source

Societal and Healthcare Costs of Post-IDFS Events Following Adjuvant Ribociclib Plus an Aromatase Inhibitor (AI) Versus AI Alone in Pre- and Postmenopausal Women with Early HR+/HER2- Breast Cancer in Canada. [PDF]

Curr Oncol
Soliman D, Brezden-Masley C, Sehdev S, Sabater Anaya N, Boukouvalas S, Vincken T.   +5 more
europepmc   +1 more source

Molecular Diagnosis in Children With Febrile Seizures: Beyond the Conventional Clinical Classification

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Febrile seizures (FS) are currently classified as simple or complex primarily to describe seizure characteristics, with limited ability to identify the underlying etiology. We evaluated whether molecular diagnosis could complement conventional classification and improve the diagnosis and management of FS.
Jia Wang, Mengna Zhang, Yangyang Wang, Xiuyu Shi, Baoguang Li, Xiuxia Wang, Dan Sun, Sanqing Xu, Jianbo Zhao, Lijun Du, Qiming Pang, Xiaoming Liu, Chunhui Tang, Xiaohua Li, Jiuwei Li, Yanli Ma, Jianxiang Liao, Gulixian Abudureyimu, Jianmin Liang, Yuan Wang, De Wu, Jian Wu, Liping Zou   +22 more
wiley   +1 more source

PMU27 1-YEAR POSTTRANSPLANT DIRECT NON-MEDICAL AND INDIRECT COSTS FOR RECIPIENTS AND CAREGIVERS IN THAILAND: A SURVEY FROM 5 TRANSPLANT CENTERS [PDF]

Value in Health, 2019
openaire   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

National-level estimation of long-term economic burden for lung cancer patients in China. [PDF]

Front Public Health
Sun C, Yan W, Guo W, Liu Y, Liu G.
europepmc   +1 more source

Race and Household Income Are Associated With Disease Outcomes in Pediatric Patients With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis Hospitalized in the United States

Arthritis Care &Research, EarlyView.
Objective Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race and ethnicity and household income are associated with severe AAV disease and renal outcomes among
Roberto Alejandro Valdovinos, William Daniel Soulsby III, Emily von Scheven   +2 more
wiley   +1 more source